Cholestasis is a condition characterized by the abnormal production or excretion of bile, and
it can be induced by a variety of causes, the factors of which are extremely complex …

Since its introduction into clinical practice, parenteral nutrition has revolutionized the care of
premature neonates. Serum transaminase and bilirubin levels are commonly elevated in …

OBJECTIVE: To test the hypothesis that implementation of a marked reduction in
intravenous fat will result in reversal of parenteral nutrition–associated liver disease …

OBJECTIVE: The aim of this study was to review evidence-based data addressing key
clinical questions regarding parenteral nutrition–associated cholestasis (PNAC) and …

Prevention of parenteral nutrition-associated liver disease:... : Current Opinion in Organ
Transplantation Prevention of parenteral nutrition-associated liver disease: lipid …

Parenteral nutrition (PN) is a life-saving nutritional support for a large population of
hospitalized infants, and lipids make a substantial contribution to their energy and essential …

Oxidative stress is caused by an imbalance between the production of reactive oxygen (free
radicals) and the body's ability (antioxidant capacity) to readily detoxify the reactive …

Objective. To determine whether cholecystokinin-octapeptide (CCK-OP) would prevent or
ameliorate parenteral nutrition-associated cholestasis (PNAC) among high-risk neonates …

Total parenteral nutrition (TPN) induces a high rate of liver disease in infants, yet the
pathogenesis remains elusive. We used neonatal piglets as an animal model to assess …

Intestinal failure-associated liver disease (IFALD) is a common complication of long-term
parenteral nutrition that is associated with significant morbidity and mortality. It is mainly …