Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics

DV Bhalani, B Nutan, A Kumar, AK Singh Chandel - Biomedicines, 2022 - mdpi.com
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

Functional hydrogels for treatment of chronic wounds

I Firlar, M Altunbek, C McCarthy, M Ramalingam… - Gels, 2022 - mdpi.com
Chronic wounds severely affect 1–2% of the population in developed countries. It has been
reported that nearly 6.5 million people in the United States suffer from at least one chronic …

Recent advancements in materials and coatings for biomedical implants

KK Amirtharaj Mosas, AR Chandrasekar, A Dasan… - Gels, 2022 - mdpi.com
Metallic materials such as stainless steel (SS), titanium (Ti), magnesium (Mg) alloys, and
cobalt-chromium (Co-Cr) alloys are widely used as biomaterials for implant applications …

pH-responsive nanocarriers in cancer therapy

NM AlSawaftah, NS Awad, WG Pitt, GA Husseini - Polymers, 2022 - mdpi.com
A number of promising nano-sized particles (nanoparticles) have been developed to
conquer the limitations of conventional chemotherapy. One of the most promising methods is …

Prospective applications of two-dimensional materials beyond laboratory frontiers: A review

P Kumbhakar, JS Jayan, AS Madhavikutty, PR Sreeram… - IScience, 2023 - cell.com
The development of nanotechnology has been advancing for decades and gained
acceleration in the 21st century. Two-dimensional (2D) materials are widely available, giving …

Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

Q Meng, S Zhong, L Xu, J Wang, Z Zhang, Y Gao… - Carbohydrate …, 2022 - Elsevier
The unique natural advantages of polysaccharide materials have attracted attention in
biomedical applications. The abundant modifiable functional groups on the polysaccharide …

Nanocellulose-based composite materials used in drug delivery systems

Y Huo, Y Liu, M Xia, H Du, Z Lin, B Li, H Liu - Polymers, 2022 - mdpi.com
Nanocellulose has lately emerged as one of the most promising “green” materials due to its
unique properties. Nanocellulose can be mainly divided into three types, ie, cellulose …

Dextran based amphiphilic nano-hybrid hydrogel system incorporated with curcumin and cerium oxide nanoparticles for wound healing

SM Andrabi, S Majumder, KC Gupta… - Colloids and Surfaces B …, 2020 - Elsevier
During injury or diseased condition, wound dressing fails to properly integrate or repair the
tissue and restore its function due to various factors like poor bioavailability, systemic …

PH responsive polyurethane for the advancement of biomedical and drug delivery

RYH Tan, CS Lee, MR Pichika, SF Cheng, KY Lam - Polymers, 2022 - mdpi.com
Due to the specific physiological pH throughout the human body, pH-responsive polymers
have been considered for aiding drug delivery systems. Depending on the surrounding pH …

Strategies to obtain encapsulation and controlled release of small hydrophilic molecules

Q Li, X Li, C Zhao - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
The therapeutic effect of small hydrophilic molecules is limited by the rapid clearance from
the systemic circulation or a local site of administration. The unsuitable pharmacokinetics …