Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

[HTML][HTML] Emergence of antibiotic resistance Pseudomonas aeruginosa in intensive care unit; a critical review

P Pachori, R Gothalwal, P Gandhi - Genes & diseases, 2019 - Elsevier
The emergence of antibiotic resistant bacteria in the healthcare is a serious concern. In the
Healthcare premises precisely intensive care unit are major sources of microbial diversity …

Colistin: an update on the antibiotic of the 21st century

S Biswas, JM Brunel, JC Dubus… - Expert review of anti …, 2012 - Taylor & Francis
The emergence of multidrug-resistant Gram-negative bacteria that cause nosocomial
infections is a growing problem worldwide. Colistin was first introduced in 1952 and was …

Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms

P Baker, PJ Hill, BD Snarr, N Alnabelseya… - Science …, 2016 - science.org
Bacterial biofilms present a significant medical challenge because they are recalcitrant to
current therapeutic regimes. A key component of biofilm formation in the opportunistic …

Treatment of Wound Infections in a Mouse Model Using Zn2+-Releasing Phage Bound to Gold Nanorods

H Peng, D Rossetto, SS Mansy, MC Jordan, KP Roos… - ACS …, 2022 - ACS Publications
Infections caused by drug-resistant bacteria, particularly Gram-negative organisms, are
increasingly difficult to treat using antibiotics. A potential alternative is “phage therapy”, in …

Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

TH Jakobsen, M van Gennip, RK Phipps… - Antimicrobial agents …, 2012 - Am Soc Microbiol
In relation to emerging multiresistant bacteria, development of antimicrobials and new
treatment strategies of infections should be expected to become a high-priority research …

Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections

J Li, RL Nation, JD Turnidge, RW Milne… - The Lancet infectious …, 2006 - thelancet.com
Increasing multidrug resistance in Gram-negative bacteria, in particular Pseudomonas
aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, presents a critical …

Antibacterial activity of iron oxide, iron nitride, and tobramycin conjugated nanoparticles against Pseudomonas aeruginosa biofilms

LM Armijo, SJ Wawrzyniec, M Kopciuch… - Journal of …, 2020 - Springer
Background Novel methods are necessary to reduce morbidity and mortality of patients
suffering from infections with Pseudomonas aeruginosa. Being the most common infectious …

[HTML][HTML] Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium

N Mesaros, P Nordmann, P Plésiat… - Clinical microbiology …, 2007 - Elsevier
Pseudomonas aeruginosa is a major cause of nosocomial infections. This organism shows
a remarkable capacity to resist antibiotics, either intrinsically (because of constitutive …

Metallo-sideromycin as a dual functional complex for combating antimicrobial resistance

C Wang, Y Xia, R Wang, J Li, CL Chan… - Nature …, 2023 - nature.com
The rapid emergence of antimicrobial resistance (AMR) pathogens highlights the urgent
need to approach this global burden with alternative strategies. Cefiderocol (Fetroja®) is a …