Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European …

P Ljungman, R de la Camara, C Robin… - The Lancet infectious …, 2019 - thelancet.com
Cytomegalovirus is one of the most important infections to occur after allogeneic
haematopoietic stem cell transplantation (HSCT), and an increasing number of reports …

Immune reconstitution after allogeneic hematopoietic stem cell transplantation

J Ogonek, M Kralj Juric, S Ghimire… - Frontiers in …, 2016 - frontiersin.org
The timely reconstitution and regain of function of a donor-derived immune system is of
utmost importance for the recovery and long-term survival of patients after allogeneic …

Letermovir prophylaxis for cytomegalovirus in hematopoietic-cell transplantation

FM Marty, P Ljungman, RF Chemaly… - … England Journal of …, 2017 - Mass Medical Soc
Background Cytomegalovirus (CMV) infection remains a common complication after
allogeneic hematopoietic-cell transplantation. Letermovir is an antiviral drug that inhibits the …

Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

AM Leen, CM Bollard, AM Mendizabal… - Blood, The Journal …, 2013 - ashpublications.org
Virus-specific T cell (VST) lines could provide useful antiviral prophylaxis and treatment of
immune-deficient patients if it were possible to avoid the necessity of generating a separate …

[HTML][HTML] A randomized, double-blind, placebo-controlled phase 3 trial of oral brincidofovir for cytomegalovirus prophylaxis in allogeneic hematopoietic cell …

FM Marty, DJ Winston, RF Chemaly, KM Mullane… - Biology of Blood and …, 2019 - Elsevier
Cytomegalovirus (CMV) infection is a common complication of allogeneic hematopoietic cell
transplantation (HCT). In this trial, we randomized adult CMV-seropositive HCT recipients …

Overview of the diagnosis of cytomegalovirus infection

SA Ross, Z Novak, S Pati… - Infectious Disorders-Drug …, 2011 - ingentaconnect.com
Cytomegalovirus (CMV) is recognized as the most common congenital viral infection in
humans and an important cause of morbidity and mortality in immunocompromised hosts …

Antiviral drug resistance of human cytomegalovirus

NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation

FM Marty, DJ Winston, SD Rowley… - … England Journal of …, 2013 - Mass Medical Soc
Background The use of available antiviral agents for the prevention of cytomegalovirus
(CMV) disease is limited by frequent toxic effects and the emergence of resistance. CMX001 …

How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation

H Einsele, P Ljungman… - Blood, The Journal of the …, 2020 - ashpublications.org
Cytomegalovirus (CMV) reactivation remains one of the most common and life-threatening
infectious complications following allogeneic hematopoietic stem cell transplantation …

Comparison of droplet digital PCR to real-time PCR for quantitative detection of cytomegalovirus

RT Hayden, Z Gu, J Ingersoll, D Abdul-Ali… - Journal of clinical …, 2013 - Am Soc Microbiol
Quantitative real-time PCR (QRT-PCR) has been widely implemented for clinical viral load
testing, but a lack of standardization and relatively poor precision have hindered its …