[HTML][HTML] Regulation of exosome production and cargo sorting

H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

The RNA methyltransferase NSUN2 and its potential roles in cancer

A Chellamuthu, SG Gray - Cells, 2020 - mdpi.com
5-methylcytosine is often associated as an epigenetic modifier in DNA. However, it is also
found increasingly in a plethora of RNA species, predominantly transfer RNAs, but …

RNA 5-methylcytosine modification and its emerging role as an epitranscriptomic mark

Y Gao, J Fang - RNA biology, 2021 - Taylor & Francis
methylcytosine (m5C) is identified as an abundant and conserved modification in various
RNAs, including tRNAs, mRNAs, rRNAs, and other non-coding RNAs. The application of …

RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

YA Kim, T Siddiqui, J Blaze, MI Cosacak, T Winters… - Acta …, 2023 - Springer
Epitranscriptomic regulation adds a layer of post-transcriptional control to brain function
during development and adulthood. The identification of RNA-modifying enzymes has …

Prognostic Value of an m5C RNA Methylation Regulator-Related Signature for Clear Cell Renal Cell Carcinoma

H Li, H Jiang, Z Huang, Z Chen… - Cancer Management and …, 2021 - Taylor & Francis
Purpose Clear cell renal cell carcinoma (ccRCC) is highly heterogeneous and is one of the
most lethal types of cancer within the urinary system. Aberrant expression of 5 …

Extracellular Vesicles: New Population Analysis Methods and Their Role as Messengers in Tumor-Stroma Communication

JTC Maia - 2021 - search.proquest.com
Abstract Extracellular Vesicles (EVs) are membrane vesicles released by virtually all cells,
that are currently emerging as important circulating carriers of biological information. EVs …

NSun2 deficiency promotes tau hyperphosphorylation and neurodegeneration through epitranscriptomic regulation of miR-125b

YA Kim, J Blaze, T Winters, A Kumar, E Tein, AA Sproul… - bioRxiv, 2021 - biorxiv.org
Overproduction or suppression of certain microRNAs (miRNAs) in Alzheimer's disease (AD)
brains promote alterations in tau proteostasis and neurodegeneration. However, the …