Salamanders have been hailed as champions of regeneration, exhibiting a remarkable
ability to regrow tissues, organs and even whole body parts, eg their limbs. As such …

Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

The molecular mechanism underlying brain regeneration in vertebrates remains elusive. We
performed spatial enhanced resolution omics sequencing (Stereo-seq) to capture spatially …

Loss of regenerative capacity is a normal part of aging. However, some organisms, such as
the Mexican axolotl, retain striking regenerative capacity throughout their lives. Moreover …

Throughout the animal kingdom regenerative ability varies greatly from species to species,
and even tissue to tissue within the same organism. The sheer diversity of structures and …

While the axolotl's ability to completely regenerate amputated limbs is well known and
studied, the mechanism of axolotl bone fracture healing remains poorly understood. One …

Formation of a specialized wound epidermis is required to initiate salamander limb
regeneration. Yet little is known about the roles of the early wound epidermis during the …

Background The axolotl is a key model to study appendicular regeneration. The limb
complexity resembles that of humans in structure and tissue components; however, axolotl …

Exhibiting extreme regenerative abilities which extend to complex organs and entire limbs,
salamanders have long served as research models for understanding the basis of vertebrate …

Salamander limb regeneration is an accurate process which gives rise exclusively to the
missing structures, irrespective of the amputation level. This suggests that cells in the stump …