Abstract Purpose of Review To review the burden of osteoporosis (OP) in rheumatoid
arthritis (RA) and to describe the OP screening strategies applied in RA. Recent Findings RA …

Rheumatoid arthritis is characterized by synovial inflammation and irreversible bone
erosions, both highlighting the immense reciprocal relationship between the immune and …

Osteoporosis is a chronic disease characterized by an increased risk of fragility fracture.
Patients affected by rheumatic diseases are at greater risk of developing osteoporosis. The …

Over the past two decades, the field of osteoimmunology has emerged in response to a
range of evidence demonstrating the reciprocal relationship between the immune system …

The term osteoimmunology describes an interdisciplinary research field that links the
investigation of osteology (bone cells) with immunology. The crosstalk between innate and …

Generalized bone loss (osteoporosis) and fragility fractures can occur in rheumatic and
musculoskeletal diseases including rheumatoid arthritis and spondyloarthritis (SpA; …

The aim of this research was to determine any correlations between Dickkopf-1 serum levels
(Dkk-1, a natural inhibitor of the Wnt signaling pathway promoting osteoclastogenesis) and …

Bone erosion is a debilitating pathological process of osteopathic disorder like rheumatoid
arthritis (RA). Current treatment strategies render low disease activity but with disease …

Abstract Dickkopf-1 (DKK-1) is mostly known as a mature inhibitor of classic Wnt signaling
pathways, which plays a critically role in regulating bone formation and bone metastasis. In …

Bone is an extremely dynamic and adaptive tissue, whose metabolism and homeostasis is
influenced by many different hormonal, mechanical, nutritional, immunological and …