From its uses in ancient civilisations, copper has an established history as an antimicrobial
agent. Extensive research has determined the efficacy and mechanism of copper's …

The pathogenic bacterium Staphylococcus aureus is the most common pathogen isolated in
skin-and-soft-tissue infections (SSTIs) in the United States. Most S. aureus SSTIs are caused …

BCG vaccination in children protects against heterologous infections and improves survival
independently of tuberculosis prevention. The phase III ACTIVATE trial assessed whether …

The US burden of acute skin infections is substantial. While Staphylococcus aureus and
Streptococcus spp. are the most common causes, gram-negative bacteria and mixed …

With the increase of antibiotic resistance currently available at an alarming rate, new
improved films of Chitosan (CS) have been achieved with different levels of Tigecycline …

Staphylococcus aureus, a ubiquitous pathogen, is the most common bacteria involved in
purulent acute bacterial skin and skin structure infections (ABSSSI) 1. Over the years …

Complicated skin and soft tissue infections (cSSTIs) represent the severe form of infectious
disease that involves deeper soft tissues. Involvement of methicillin-resistant …

Background Delafloxacin is an intravenous (IV)/oral anionic fluoroquinolone with activity
against gram-positive (including methicillin-resistant Staphylococcus aureus [MRSA]), gram …

Background Pathogen resistance and safety concerns limit oral antibiotic options for the
treatment of acute bacterial skin and skin structure infections (ABSSSI). We aimed to …

Background Delafloxacin is an investigational anionic fluoroquinolone in development for
oral or intravenous administration for the treatment of infections caused by Gram-positive …