Evaluation and management of heart failure with preserved ejection fraction

BA Borlaug - Nature Reviews Cardiology, 2020 - nature.com
Heart failure with preserved ejection fraction (HFpEF) has grown to become the dominant
form of heart failure worldwide, in tandem with ageing of the general population and the …

Heart failure with preserved ejection fraction in perspective

MA Pfeffer, AM Shah, BA Borlaug - Circulation research, 2019 - Am Heart Assoc
Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …

Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial

JA Ezekowitz, E Colin-Ramirez, H Ross, J Escobedo… - The Lancet, 2022 - thelancet.com
Background Dietary restriction of sodium has been suggested to prevent fluid overload and
adverse outcomes for patients with heart failure. We designed the Study of Dietary …

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection
fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge …

Dietary metabolism, the gut microbiome, and heart failure

WHW Tang, DY Li, SL Hazen - Nature Reviews Cardiology, 2019 - nature.com
Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …

Phenotype-specific treatment of heart failure with preserved ejection fraction: a multiorgan roadmap

SJ Shah, DW Kitzman, BA Borlaug, L Van Heerebeek… - Circulation, 2016 - Am Heart Assoc
Heart failure (HF) with preserved ejection fraction (EF; HFpEF) accounts for 50% of HF
cases, and its prevalence relative to HF with reduced EF continues to rise. In contrast to HF …

Hypertension management in patients with cardiovascular comorbidities

L Lauder, F Mahfoud, M Azizi, DL Bhatt… - European Heart …, 2023 - academic.oup.com
Arterial hypertension is a leading cause of death globally. Due to ageing, the rising
incidence of obesity, and socioeconomic and environmental changes, its incidence …

The role of ventricular–arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of …

I Ikonomidis, V Aboyans, J Blacher… - European journal of …, 2019 - Wiley Online Library
Ventricular–arterial coupling (VAC) plays a major role in the physiology of cardiac and aortic
mechanics, as well as in the pathophysiology of cardiac disease. VAC assessment …

Contributory risk and management of comorbidities of hypertension, obesity, diabetes mellitus, hyperlipidemia, and metabolic syndrome in chronic heart failure: a …

B Bozkurt, D Aguilar, A Deswal, SB Dunbar… - Circulation, 2016 - Am Heart Assoc
Elevated levels of diastolic BP and especially systolic BP (SBP) are major risk factors for the
development of HF. 18, 19 One of the most impactful observations from the Framingham …

Effects of the Dietary Approach to Stop Hypertension (DASH) diet on cardiovascular risk factors: a systematic review and meta-analysis

M Siervo, J Lara, S Chowdhury, A Ashor… - British Journal of …, 2015 - cambridge.org
The Dietary Approach to Stop Hypertension (DASH) is recommended to lower blood
pressure (BP), but its effects on cardiometabolic biomarkers are unclear. A systematic review …