Exercise in heart failure patients supported with a left ventricular assist device

MH Jung, F Gustafsson - The Journal of Heart and Lung Transplantation, 2015 - Elsevier
After implantation of a continuous-flow left ventricular assist device (CF-LVAD), exercise
capacity in heart failure patients remains reduced with peak oxygen uptake (peak VO 2) …

Living without a pulse: the vascular implications of continuous-flow left ventricular assist devices

SN Purohit, WK Cornwell III, JD Pal… - Circulation: Heart …, 2018 - Am Heart Assoc
Pulsatility seems to have a teleological role because evolutionary hierarchy favors higher
ordered animals with more complex, multichamber circulatory systems that generate higher …

Improved survival and decreasing incidence of adverse events with the HeartMate II left ventricular assist device as bridge-to-transplant therapy

R John, F Kamdar, K Liao, M Colvin-Adams… - The Annals of thoracic …, 2008 - Elsevier
BACKGROUND: Pulsatile left ventricular assist devices (LVADs) are effective as bridge-to-
transplant therapy, but they are limited by their large size and lack of durability. Smaller …

Further peripheral vascular dysfunction in heart failure patients with a continuous-flow left ventricular assist device: the role of pulsatility

MAH Witman, RS Garten, JR Gifford, HJ Groot… - JACC: Heart Failure, 2015 - jacc.org
Objectives: Using flow-mediated vasodilation (FMD) and reactive hyperemia (RH), this study
aimed to provide greater insight into left ventricular assist device (LVAD)–induced changes …

Sympathetic neural and hemodynamic responses to upright tilt in patients with pulsatile and nonpulsatile left ventricular assist devices

DW Markham, Q Fu, MD Palmer… - Circulation: Heart …, 2013 - Am Heart Assoc
Background—Left ventricular assist devices (LVADs) are now widely accepted as an option
for patients with advanced heart failure. First-generation devices were pulsatile, but they had …

End-organ function in patients on long-term circulatory support with continuous-or pulsatile-flow assist devices

B Radovancevic, B Vrtovec, E de Kort… - The Journal of heart and …, 2007 - Elsevier
BACKGROUND: Limited data exist about the long-term effects of continuous-flow vs
pulsatile-flow left ventricular assist devices (LVADs) on end-organ function. METHODS: We …

Effects of centrifugal, axial, and pulsatile left ventricular assist device support on end-organ function in heart failure patients

F Kamdar, A Boyle, K Liao, M Colvin-adams… - The Journal of heart and …, 2009 - Elsevier
PURPOSE: Newer continuous-flow left ventricular assist devices (LVAD) have the
advantage of smaller size and increased durability. Questions remain regarding the safety …

Vasoplegia following orthotopic heart transplantation: prevalence, predictors and clinical outcomes

RJ Batchelor, W Nathan, DH Liu, C Chua… - Journal of Cardiac …, 2022 - Elsevier
Background Patients undergoing heart transplant are at high risk for postoperative
vasoplegia. Despite its frequency and association with poor clinical outcomes, there remains …

Lessons learned from experience with over 100 consecutive HeartMate II left ventricular assist devices

R John, F Kamdar, P Eckman, M Colvin-Adams… - The Annals of thoracic …, 2011 - Elsevier
BACKGROUND: Continuous-flow left ventricular assist devices (LVADs) such as the
HeartMate II have become the therapy of choice in patients with end-stage heart failure. The …

Left ventricular assist devices and the kidney

DW Ross, GR Stevens, R Wanchoo… - Clinical Journal of the …, 2018 - journals.lww.com
Left ventricular assist devices (LVADs) are common and implantation carries risk of AKI.
LVADs are used as a bridge to heart transplantation or as destination therapy. Patients with …