[HTML][HTML] Snake venoms in drug discovery: Valuable therapeutic tools for life saving
Animal venoms are used as defense mechanisms or to immobilize and digest prey. In fact,
venoms are complex mixtures of enzymatic and non-enzymatic components with specific …
venoms are complex mixtures of enzymatic and non-enzymatic components with specific …
Antitumoral activity of snake venom proteins: new trends in cancer therapy
LA Calderon, JC Sobrinho, KD Zaqueo… - BioMed research …, 2014 - Wiley Online Library
For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …
[HTML][HTML] Anticancer activity of toxins from bee and snake venom—An overview on ovarian cancer
MA Moga, OG Dimienescu, CA Arvătescu, P Ifteni… - Molecules, 2018 - mdpi.com
Cancer represents the disease of the millennium, a major problem in public health. The
proliferation of tumor cells, angiogenesis, and the relationship between the cancer cells and …
proliferation of tumor cells, angiogenesis, and the relationship between the cancer cells and …
Mechanistic insights of snake venom disintegrins in cancer treatment
Snake venoms are a potential source of various enzymatic and non-enzymatic compounds
with a defensive role for the host. Various peptides with significant medicinal properties have …
with a defensive role for the host. Various peptides with significant medicinal properties have …
[HTML][HTML] Phospholipase A2 Isolated from the Venom of Crotalus durissus terrificus Inactivates Dengue virus and Other Enveloped Viruses by Disrupting the Viral …
VD Muller, RO Soares, NN dos Santos-Junior… - PLoS …, 2014 - journals.plos.org
The Flaviviridae family includes several virus pathogens associated with human diseases
worldwide. Within this family, Dengue virus is the most serious threat to public health …
worldwide. Within this family, Dengue virus is the most serious threat to public health …
Harnessing snake venom phospholipases A2 to novel approaches for overcoming antibiotic resistance
JR Almeida, ALV Palacios, RSP Patiño… - Drug development …, 2019 - Wiley Online Library
The emergence of antibiotic resistance drives an essential race against time to reveal new
molecular structures capable of addressing this alarming global health problem. Snake …
molecular structures capable of addressing this alarming global health problem. Snake …
[HTML][HTML] Antibacterial properties of snake venom components
An increasing problem in the field of health protection is the emergence of drug-resistant
and multi-drug-resistant bacterial strains. They cause a number of infections, including …
and multi-drug-resistant bacterial strains. They cause a number of infections, including …
[HTML][HTML] CoaTx-II, a new dimeric Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and …
Snake venoms are rich and intriguing sources of biologically-active molecules that act on
target cells, modulating a diversity of physiological functions and presenting promising …
target cells, modulating a diversity of physiological functions and presenting promising …
[HTML][HTML] Bactericidal effects of snake venom phospholipases A2: a systematic review and analysis of minimum inhibitory concentration
Background: Infections caused by multi-drug resistance (MDR) strains are potentially fatal
public health issues worldwide that need pressing attention. Previous reports suggested …
public health issues worldwide that need pressing attention. Previous reports suggested …
Understanding the mechanism of action of peptide (p-BthTX-I) 2 derived from C-terminal region of phospholipase A2 (PLA2)-like bothropstoxin-I on Gram-positive and …
NA Santos-Filho, LM de Freitas, CT Dos Santos… - Toxicon, 2021 - Elsevier
Based on the antimicrobial activity of bothropstoxin-I (BthTX-I) and on the premise that a C-
terminal peptide of Lys49 myotoxin can reproduce the antimicrobial activity of the parent …
terminal peptide of Lys49 myotoxin can reproduce the antimicrobial activity of the parent …