Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable
membrane environment for proteins to being embedded in to detailed roles in complicated …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Solid-state nuclear magnetic resonance (SSNMR) spectroscopy elucidates membrane
protein structures and dynamics in atomic detail to yield mechanistic insights. By …

Magic angle spinning (MAS) NMR studies of amyloid and membrane proteins and large
macromolecular complexes are an important new approach to structural biology. However …

Membrane proteins present a challenge for structural biology. In this article, we review some
of the recent developments that advance the application of NMR to membrane proteins, with …

The voltage-dependent anion channel (VDAC), the most abundant protein in the outer
mitochondrial membrane, is responsible for the transport of all ions and metabolites into and …

The voltage-dependent anion channel (VDAC) is one of the most highly abundant proteins
found in the outer mitochondrial membrane, and was one of the earliest discovered. Here …

The cellular process of intrinsic apoptosis relies on the peroxidation of mitochondrial lipids
as a critical molecular signal. Lipid peroxidation is connected to increases in mitochondrial …

An intrinsically disordered neuronal protein α-synuclein (αSyn) is known to cause
mitochondrial dysfunction, contributing to loss of dopaminergic neurons in Parkinson's …

While an increasing number of structural biology studies successfully demonstrate the
power of high-resolution structures and dynamics of membrane proteins in fully …