Deregulated inflammatory response plays a pivotal role in the initiation, development and
progression of tumours. Potential molecular mechanism (s) that drive the establishment of …

Inflammation is a biological function which triggered after the mechanical tissue disruption or
from the responses by the incidence of physical, chemical or biological negotiator in body …

Diosgenin (DSG) is a naturally occurring steroidal saponin with a variety of biological
activities that is also an important precursor for the synthesis of various steroidal drugs. The …

Ethnopharmacological relevance Citrus fruit peels are traditionally used in folk medicine for
the treatment of skin disorders but it lacks proper pharmacological intervention. Citrus limetta …

Dioscorea pentaphylla L., a wild tuber is used both as food and medicines among different
ethnic groups of Similipal Biosphere Reserve, India. Tubers are used against skin infections …

Liquiritigenin (LTG) and its bioprecursor isoliquiritigenin (ISL), the main bioactives from roots
of Glycyrrhiza genus are progressively documented as a potential pharmacological agent for …

In order to produce an effective and multi-targeted clinical drug that could prevent
progressive neurodegeneration, a series of diosgenin carbamate derivatives were …

Thirty-two new diosgenin derivatives were designed, synthesized, and evaluated for their
cytotoxic activities in three human cancer cell lines (A549, MCF-7, and HepG2) and normal …

A series of novel diosgenin (DSG) and tigogenin (TGG) derivatives with diosgenin or
tigogenin steroid aglycons linked to levulinic and 3, 4–dihydroxycinnamic acids, dipeptides …

Prostate cancer is one of the most common cancers in men. Diosgenin and related
compounds are potential cytotoxic agents. Twelve diverse analogues of long chain fatty …