An Integrated In Silico and In Vitro Approach for the Identification of Natural Products Active against SARS-CoV-2

R Pennisi, D Gentile, A Rescifina, E Napoli, P Trischitta… - Biomolecules, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has provoked a global health crisis due to the absence of a …

1, 2-Dibenzoylhydrazine as a multi-inhibitor compound: A morphological and docking study

V Patamia, G Floresta, C Zagni, V Pistarà… - International Journal of …, 2023 - mdpi.com
In the framework of the multitarget inhibitor study, we report an in silico analysis of 1, 2-
dibenzoylhydrazine (DBH) with respect to three essential receptors such as the ecdysone …

Heparan sulfate and enoxaparin interact at the interface of the spike protein of HCoV-229E but not with HCoV-OC43

V Fuochi, G Floresta, R Emma, V Patamia, M Caruso… - Viruses, 2023 - mdpi.com
It is known that the spike protein of human coronaviruses can bind to a secondary receptor,
or coreceptor, to facilitate the virus entry. While HCoV-229E uses human aminopeptidase N …

In Silico Therapeutic Study: The Next Frontier in the Fight against SARS-CoV-2 and Its Variants

CR Wei, Z Basharat, GC Lang'at - Drugs and Drug Candidates, 2024 - mdpi.com
COVID-19 has claimed around 7 million lives (from December 2019–November 2023)
worldwide and continues to impact global health. SARS-CoV-2, the virus causing COVID-19 …

Phytoconstituents as potential therapeutic agents against COVID-19: a computational study on inhibition of SARS-CoV-2 main protease

A Alsrhani, A Farhana, YS Khan… - Journal of …, 2024 - Taylor & Francis
Abstract The Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS‑CoV‑2) has become a global health crisis, and …

Antiviral efficacy of heparan sulfate and enoxaparin sodium against SARS‐CoV‐2

V Fuochi, S Furnari, G Floresta, V Patamia… - Archiv der …, 2024 - Wiley Online Library
As the world transitions from the acute phase of the COVID‐19 pandemic caused by SARS‐
CoV‐2, the scientific community continues to explore various therapeutic avenues to control …

[HTML][HTML] Antiviral Efficacy of Coridothymus capitatus Essential Oil Against HSV-1 and HSV-2

V Fuochi, PM Furneri, S Furnari, A Garozzo - Life, 2024 - mdpi.com
Coridothymus capitatus is a perennial herb with aromatic leaves and flowers, distinct from
Thymus vulgaris in its chemical composition, resulting in a unique Thymus Essential Oil …

Antiviral Efficacy of Heparan Sulfate and Enoxaparin Sodium against SARS-CoV-2: An In-Vitro/in-Silico Model

V Fuochi, S Furnari, G Floresta, V Patamia, C Zagni… - 2023 - preprints.org
SARS-CoV-2 attachment and entry inside mammalian cells is mainly mediated by human
angiotensin-converting enzyme 2 (ACE2) and its interaction with spike protein. However, it is …