HIV-1: fifteen proteins and an RNA

AD Frankel, JAT Young - Annual review of biochemistry, 1998 - annualreviews.org
Human immunodeficiency virus type 1 is a complex retrovirus encoding 15 distinct proteins.
Substantial progress has been made toward understanding the function of each protein, and …

HIV-1 gag proteins: diverse functions in the virus life cycle

EO Freed - Virology, 1998 - Elsevier
The Gag proteins of HIV-1, like those of other retroviruses, are necessary and sufficient for
the assembly of virus-like particles. The roles played by HIV-1 Gag proteins during the life …

Capsid is a dominant determinant of retrovirus infectivity in nondividing cells

M Yamashita, M Emerman - Journal of virology, 2004 - Am Soc Microbiol
ABSTRACT A major difference between lentiviruses such as human immunodeficiency virus
(HIV) and most other retroviruses is their ability to productively infect nondividing cells. We …

CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A

T Pushkarsky, G Zybarth, L Dubrovsky… - Proceedings of the …, 2001 - National Acad Sciences
Cyclophilin A (CyPA) is specifically incorporated into the virions of HIV-1 and has been
shown to enhance significantly an early step of cellular HIV-1 infection. Our preliminary …

[HTML][HTML] HIV‐1 infection of non‐dividing cells: evidence that the amino‐terminal basic region of the viral matrix protein is important for Gag processing but not for post …

RAM Fouchier, BE Meyer, JHM Simon, U Fischer… - The EMBO …, 1997 - embopress.org
Human immunodeficiency virus type‐1 (HIV‐1) is able to infect non‐dividing cells such as
tissue macrophages productively because post‐entry viral nucleoprotein complexes are …

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton

A Bukrinskaya, B Brichacek, A Mann… - The Journal of …, 1998 - rupress.org
After interaction of human immunodeficiency virus type 1 (HIV-1) virions with cell surface
receptors, a series of poorly characterized events results in establishment of a viral reverse …

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration …

M Llano, M Vanegas, O Fregoso, D Saenz… - Journal of …, 2004 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1), feline immunodeficiency virus (FIV), and
Moloney murine leukemia virus (MoMLV) integrases were stably expressed to determine …

Nuclear import and export of viruses and virus genomes

GR Whittaker, A Helenius - Virology, 1998 - Elsevier
Many viruses replicate in the nucleus of their animal and plant host cells. Nuclear import,
export, and nucleo-cytoplasmic shuttling play a central role in their replication cycle …

[HTML][HTML] Efficient HIV‐1 replication can occur in the absence of the viral matrix protein

H Reil, AA Bukovsky, HR Gelderblom… - The EMBO …, 1998 - embopress.org
Matrix (MA), a major structural protein of retroviruses, is thought to play a critical role in
several steps of the HIV‐1 replication cycle, including the plasma membrane targeting of …

Viral entry into the nucleus

GR Whittaker, M Kann, A Helenius - Annual review of cell and …, 2000 - annualreviews.org
▪ Abstract Because many viruses replicate in the nucleus of their host cells, they must have
ways of transporting their genome and other components into and out of this compartment …