The plasma membrane of cells contains a diverse array of lipids that provide important
structural and biological features. Glycolipids are typically a minor component of the cell …

It has been two decades since the lipid raft hypothesis was first presented. Even today,
whether these nanoscale cholesterol-rich domains are present in cell membranes is not …

Sphingomyelin is a key molecule of sphingolipid metabolism, and its enzymatic breakdown
is associated with various infectious diseases. Here, we introduce trifunctional …

SARS-CoV-2 variants such as the delta or omicron variants, with higher transmission rates,
accelerated the global COVID-19 pandemic. Thus, novel therapeutic strategies need to be …

Expansion microscopy (ExM) enables super-resolution imaging of proteins and nucleic
acids on conventional microscopes. However, imaging of details of the organization of lipid …

Macrophages have important protective functions during infection with herpes simplex virus
type 1 (HSV-1). However, molecular mechanisms that restrict viral propagation and protect …

Certain fatty acids and sphingoid bases found at mucosal surfaces are known to have
antibacterial activity and are thought to play a more direct role in innate immunity against …

This chapter covers the literature published during 2017 relating to the synthesis, the
reactivity and the application of phosphines, excluding the chemistry of their metal …

Sphingolipid dysregulation is involved in a range of rare and fatal diseases as well as
common pathologies including cancer, infectious diseases or neurodegeneration. Gaining …

A simple and efficient microwave-assisted synthesis of asymmetric pentamethine cyanine
dyes with various functional groups was developed, which allows high-yielding results. The …