Neurodegenerative diseases represent nowadays one of the major health problems.
Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …

Historically, plants have been sought after as bio-factories for the production of diverse
chemical compounds that offer a multitude of possibilities to cure diseases. To combat the …

Novel carbazole-oxadiazoles were developed as new potential antibacterial agents to
combat dreadful resistance. Some target compounds displayed predominant inhibitory …

The combination of the scaffolds of the cholinesterase inhibitor huprine Y and the
antioxidant capsaicin results in compounds with nanomolar potencies toward human …

The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …

In our overall goal to overcome the limitations associated with natural products for the
management of Alzheimer's disease and to develop in-vivo active multifunctional cholinergic …

Oxidative stress is a major pathogenic factor in Alzheimer's disease, but it should not be
tackled alone rather together with other key targets to derive effective treatments. The …

Alzheimer's disease (AD) is one of the neurodegenerative diseases that led to morbidity and
mortality world-wide. It is a complex disease whose etiology is not completely known that …

Molecules capable of engaging with multiple targets associated with pathological condition
of Alzheimer's disease have proved to be potential anti-Alzheimer's agents. In our goal to …