[HTML][HTML] Ellagic acid and cilostazol ameliorate amikacin-induced nephrotoxicity in rats by downregulating oxidative stress, inflammation, and apoptosis
ZM Saeed, MI Khattab, NE Khorshid, AE Salem - Plos one, 2022 - journals.plos.org
Amikacin (AK) has the largest spectrum of aminoglycosides. However, its use is constrained
because of nephrotoxicity and ototoxicity. Ellagic acid (EA) is a polyphenol present in plants …
because of nephrotoxicity and ototoxicity. Ellagic acid (EA) is a polyphenol present in plants …
Antioxidants to prevent respiratory decline in people with Duchenne muscular dystrophy and progressive respiratory decline
L Garegnani, M Hyland, PR Rodriguez… - Cochrane database …, 2021 - cochranelibrary.com
Background Duchenne muscular dystrophy (DMD) is an X‐linked recessive disorder
characterised by progressive muscle weakness beginning in early childhood. Respiratory …
characterised by progressive muscle weakness beginning in early childhood. Respiratory …
[HTML][HTML] Oxidative Stress, Inflammation, and Activators of Mitochondrial Biogenesis: Tempol Targets in the Diaphragm Muscle of Exercise Trained-mdx Mice
HNM Silva, C Covatti, GL Rocha, DS Mizobuti… - Frontiers in …, 2021 - frontiersin.org
The mdx mouse phenotype aggravated by chronic exercise on a treadmill makes this murine
model more reliable for the study of muscular dystrophy. Thus, to better assess the Tempol …
model more reliable for the study of muscular dystrophy. Thus, to better assess the Tempol …
Cilostazol protects mice against myocardium ischemic/reperfusion injury by activating a PPARγ/JAK2/STAT3 pathway
J Li, X Xiang, X Gong, Y Shi, J Yang, Z Xu - Biomedicine & …, 2017 - Elsevier
Myocardial ischemia/reperfusion (MIR) injury causes severe arrhythmias and a high
lethality. The present study is designed to investigate the effect of cilostazol on MIR injury …
lethality. The present study is designed to investigate the effect of cilostazol on MIR injury …
Tempol improves redox status in mdx dystrophic diaphragm muscle
TA Hermes, DS Mizobuti, GL da Rocha… - International journal …, 2020 - Wiley Online Library
Oxidative stress is a critical element in relationship to the pathophysiology of Duchenne
muscular dystrophy (DMD). In the mice the diaphragm (DIA) is most resembles the …
muscular dystrophy (DMD). In the mice the diaphragm (DIA) is most resembles the …
[HTML][HTML] Tempol Supplementation Restores Diaphragm Force and Metabolic Enzyme Activities in mdx Mice
DP Burns, I Ali, C Rieux, J Healy, G Jasionek… - Antioxidants, 2017 - mdpi.com
Duchenne muscular dystrophy (DMD) is characterized by striated muscle weakness,
cardiomyopathy, and respiratory failure. Since oxidative stress is recognized as a secondary …
cardiomyopathy, and respiratory failure. Since oxidative stress is recognized as a secondary …
Vitamin E treatment decreases muscle injury in mdx mice
RD Mâncio, T de Almeida Hermes, AB Macedo… - Nutrition, 2017 - Elsevier
Objective Oxidative stress, in addition to the absence of the dystrophin protein, has been
considered an important regulator of Duchenne muscular dystrophy (DMD). Vitamin E …
considered an important regulator of Duchenne muscular dystrophy (DMD). Vitamin E …
Cilostazol attenuates oxidative stress and apoptosis in the quadriceps muscle of the dystrophic mouse experimental model
TA Hermes, RD Mâncio, DS Mizobutti… - International journal …, 2023 - Wiley Online Library
Duchenne muscular dystrophy (DMD) is the most severe and frequent form of muscular
dystrophy. The mdx mouse is one of the most widely used experimental models to …
dystrophy. The mdx mouse is one of the most widely used experimental models to …
[HTML][HTML] Dystrophic phenotype improvement in the diaphragm muscle of mdx mice by diacerhein
RD Mâncio, TA Hermes, AB Macedo, DS Mizobuti… - PLoS …, 2017 - journals.plos.org
Chronic inflammation and oxidative stress are striking features of Duchenne muscular
dystrophy disease. Diacerhein is an anthraquinone, which exhibits anti-inflammatory and …
dystrophy disease. Diacerhein is an anthraquinone, which exhibits anti-inflammatory and …
Trilobatin contributes to the improvement of myopathy in a mouse model of Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD) occurs due to genetic mutations that lead to a
deficiency in dystrophin production and consequent progressive degeneration of skeletal …
deficiency in dystrophin production and consequent progressive degeneration of skeletal …