• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

MicroRNAs (miRNAs) are small regulatory molecules post-transcriptionally suppressing
mRNA activity. Many miRNAs in various organisms have been cloned but many unknown …

The recommendations listed in this guideline are, whenever possible, evidence based. An
initial extensive evidence review, which included literature derived from research involving …

Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

In this paper the Working Group on Myocardial and Pericardial Disease proposes a revised
definition of dilated cardiomyopathy (DCM) in an attempt to bridge the gap between our …

In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Aim Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until
now technological limitations have hindered elucidation of the contribution of all clinically …

Some individuals with a particular disease-causing mutation or genotype fail to express
most if not all features of the disease in question, a phenomenon that is known as 'reduced …

Abstract Aims Lamin A/C (LMNA) mutations cause familial dilated cardiomyopathy (DCM)
with frequent conduction blocks and arrhythmias. We explored the prevalence, cardiac …

Background: Mutations in LMNA are variably expressed and may cause cardiomyopathy,
atrioventricular block (AVB), or atrial arrhythmias (AAs) and ventricular arrhythmias (VA) …