Renal blood flow, local tissue perfusion and blood oxygen content are the major
determinants of oxygen delivery to kidney tissue. Arterial pressure and segmental vascular …

Tissue hypoxia has been proposed as an important factor in the pathophysiology of both
chronic kidney disease (CKD) and acute kidney injury (AKI), initiating and propagating a …

Objectives This study aimed at developing technical recommendations for the acquisition,
processing and analysis of renal ASL data in the human kidney at 1.5 T and 3 T field …

Norepinephrine is the principal vasopressor used to restore blood pressure in sepsis, but its
effects on intrarenal oxygenation are unknown. To clarify this, we examined renal cortical …

Objectives: To determine whether there is a decrease in renal cortical or medullary perfusion
and oxygenation in a conscious large animal model of hyperdynamic septic shock with …

Renal tissue hypoperfusion and hypoxia are key elements in the pathophysiology of acute
kidney injury and its progression to chronic kidney disease. Yet, in vivo assessment of renal …

Stress-activated kinases p38 MAPK and JNK promote renal fibrosis; however, how the
pathways by which these kinases are activated in kidney disease remain poorly defined …

Over the past 20 years, there has been an increased appreciation of the long-term sequelae
of acute kidney injury (AKI) and the potential development of chronic kidney disease (CKD) …

Ischemic nephropathy consists of progressive renal function loss due to renal hypoxia,
inflammation, microvascular rarefaction, and fibrosis. We provide a literature review focused …

Iodinated contrast media (CM) can induce acute kidney injury (AKI). CM share common
iodine‐related cytotoxic features but differ considerably with regard to osmolality and …