The physics of proton therapy

WD Newhauser, R Zhang - Physics in Medicine & Biology, 2015 - iopscience.iop.org
The physics of proton therapy has advanced considerably since it was proposed in 1946.
Today analytical equations and numerical simulation methods are available to predict and …

Roadmap: proton therapy physics and biology

H Paganetti, C Beltran, S Both, L Dong… - Physics in Medicine …, 2021 - iopscience.iop.org
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Gold nanoparticles as a potent radiosensitizer: A transdisciplinary approach from physics to patient

S Penninckx, AC Heuskin, C Michiels, S Lucas - Cancers, 2020 - mdpi.com
Over the last decade, a growing interest in the improvement of radiation therapies has led to
the development of gold-based nanomaterials as radiosensitizer. Although the …

Nuclear physics in particle therapy: a review

M Durante, H Paganetti - Reports on Progress in Physics, 2016 - iopscience.iop.org
Charged particle therapy has been largely driven and influenced by nuclear physics. The
increase in energy deposition density along the ion path in the body allows reducing the …

Adaptive proton therapy

H Paganetti, P Botas, GC Sharp… - Physics in Medicine & …, 2021 - iopscience.iop.org
Radiation therapy treatments are typically planned based on a single image set, assuming
that the patient's anatomy and its position relative to the delivery system remains constant …

AAPM task group 224: comprehensive proton therapy machine quality assurance

B Arjomandy, P Taylor, C Ainsley, S Safai… - Medical …, 2019 - Wiley Online Library
Purpose: Task Group (TG) 224 was established by the American Association of Physicists in
Medicine's Science Council under the Radiation Therapy Committee and Work Group on …

Emerging technologies for cancer therapy using accelerated particles

C Graeff, L Volz, M Durante - Progress in particle and nuclear physics, 2023 - Elsevier
Cancer therapy with accelerated charged particles is one of the most valuable biomedical
applications of nuclear physics. The technology has vastly evolved in the past 50 years, the …

Review on the characteristics of radiation detectors for dosimetry and imaging

J Seco, B Clasie, M Partridge - Physics in Medicine & Biology, 2014 - iopscience.iop.org
The enormous advances in the understanding of human anatomy, physiology and pathology
in recent decades have led to ever-improving methods of disease prevention, diagnosis and …

Range verification methods in particle therapy: underlying physics and Monte Carlo modeling

AC Kraan - Frontiers in oncology, 2015 - frontiersin.org
Hadron therapy allows for highly conformal dose distributions and better sparing of organs-
at-risk, thanks to the characteristic dose deposition as function of depth. However, the quality …

A concise review on cancer treatment methods and delivery systems

E Bidram, Y Esmaeili, H Ranji-Burachaloo… - Journal of Drug Delivery …, 2019 - Elsevier
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …