Traditionally, testosterone and estrogen have been considered to be male and female sex
hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a …

Although it has been known for many years that estrogen administration has deleterious
effects on male fertility, data from transgenic mice deficient in estrogen receptors or …

Testosterone and estrogen are no longer considered male only and female only hormones.
Both hormones are important in both sexes. It was known as early as the 1930's that …

Cell migration is a process which is essential during embryonic development, throughout
adult life and in some pathological conditions. Cadherins, and more specifically the neural …

According to some estimates, at least 70% of feedstuffs and finished feeds are contaminated
with one or more mycotoxins and, due to its significant prevalence, both animals and …

The cytochrome P450 aromatase (P450arom) is the terminal enzyme responsible for the
irreversible transformation of androgens into oestrogens and is present in the endoplasmic …

Spermatogenesis occurs within the seminiferous tubules of the testis, in close association
with the somatic cells of the seminiferous epithelium, the Sertoli cells. At the completion of …

Transgenic mouse models have contributed considerably to our understanding of the
cellular and molecular mechanisms by which androgens control spermatogenesis. Cell …

In the seminiferous epithelium, Eps8 is localized to actin-based cell junctions at the blood-
testis barrier (BTB) and the apical ectoplasmic specialization (ES) in stage V–VI tubules but …

The aim of the present study was to determine the mechanisms involved in estrogen actions
in cultured rat Sertoli cells. RT-PCR detected transcripts for the estrogen receptors ESR1 …