Mortality in systemic lupus erythematosus: causes, predictors and interventions

V Ocampo-Piraquive, I Nieto-Aristizábal… - Expert review of …, 2018 - Taylor & Francis
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease
characterized by organ damage, flare-remission pattern, and increased mortality when …

B cell abnormalities in systemic lupus erythematosus and lupus nephritis—role in pathogenesis and effect of immunosuppressive treatments

DYH Yap, TM Chan - International journal of molecular sciences, 2019 - mdpi.com
Abnormalities in B cells play pivotal roles in the pathogenesis of systemic lupus
erythematosus (SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance …

[HTML][HTML] Efficacy and safety of belimumab in patients with lupus nephritis: subgroup analyses of a phase 3 randomized trial in the East Asian population

X Yu, N Chen, J Xue, CC Mok, SC Bae, X Peng… - American journal of …, 2023 - Elsevier
Rationale & Objective Belimumab improved kidney outcomes in patients with active lupus
nephritis (LN) in BLISS-LN, leading to its approval in the United States and the European …

Current treatment approach, emerging therapies and new horizons in systemic lupus erythematosus

P Athanassiou, L Athanassiou - Life, 2023 - mdpi.com
Systemic lupus erythematosus (SLE), the prototype of systemic autoimmune diseases is
characterized by extreme heterogeneity with a variable clinical course. Renal involvement …

Lupus nephritis

S Wenderfer, S Mason, C Bernal, CAA da Silva - Pediatric Nephrology, 2022 - Springer
Childhood-onset systemic lupus erythematosus (cSLE) is a subset of SLE with onset prior to
16–18 years of age. Around 15% of patients with SLE present in childhood; patients with …

ω-3 polyunsaturated fatty acid alleviates systemic lupus erythematosus by suppressing autoimmunity in a murine model

A Liu, Z Li, J Zeng, Y Peng, S Wang, X Bi, Z Zhao… - International …, 2024 - Elsevier
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune inflammatory disease
that damages multiple organs by the production of autoantibodies. Numerous research …

Elevated interleukin-25 and its association to Th2 cytokines in systemic lupus erythematosus with lupus nephritis

M Selvaraja, M Abdullah, M Arip, VK Chin, A Shah… - PloS one, 2019 - journals.plos.org
Systemic lupus erythematosus (SLE) is an autoimmune disorder that is associated with
lupus nephritis, initiated by the deposition of immune complexes in the kidney; …

Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and …

KA Owen, KA Bell, A Price, P Bachali, H Ainsworth… - Scientific reports, 2023 - nature.com
Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent
genetic component. Individuals of Asian-Ancestry (AsA) disproportionately experience more …

Prevalence and biopsychosocial factors associated with depressive symptoms among patients living with systemic lupus erythematosus in clinical settings in urban …

N Narupan, A Seeherunwong, W Pumpuang - BMC psychiatry, 2022 - Springer
Background Depressive symptoms are globally recognized as a significant mental health
problem in patients with chronic disease, particularly those with systemic lupus …

Incidence of and risk factors for active tuberculosis disease in individuals with glomerular disease: A Canadian cohort study

M Canney, HM Gunning, JC Johnston… - American Journal of …, 2023 - Elsevier
Rationale & Objective Kidney failure is an established risk factor for active tuberculosis (TB)
but the risk of TB has not been reported in specific kidney diseases. We sought to determine …