A crucial role for maternal dietary methyl donor intake in epigenetic programming and fetal growth outcomes
M McGee, S Bainbridge, B Fontaine-Bisson - Nutrition reviews, 2018 - academic.oup.com
The fetal origins of health and disease framework has identified extremes in fetal growth and
birth weight as factors associated with the lifelong generation of chronic diseases such as …
birth weight as factors associated with the lifelong generation of chronic diseases such as …
Evaluation and comparison of multi-omics data integration methods for cancer subtyping
Computational integrative analysis has become a significant approach in the data-driven
exploration of biological problems. Many integration methods for cancer subtyping have …
exploration of biological problems. Many integration methods for cancer subtyping have …
Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns
Abnormal DNA methylation is an important epigenetic regulator involving tumorigenesis.
Deciphering cancer common and specific DNA methylation patterns is essential for us to …
Deciphering cancer common and specific DNA methylation patterns is essential for us to …
BNDF methylation in mothers and newborns is associated with maternal exposure to war trauma
Background The BDNF gene codes for brain-derived neurotrophic factor, a growth factor
involved in neural development, cell differentiation, and synaptic plasticity. Present in both …
involved in neural development, cell differentiation, and synaptic plasticity. Present in both …
[HTML][HTML] DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironment
S Baluszek, P Kober, N Rusetska, M Wągrodzki… - Acta Neuropathologica …, 2023 - Springer
Chordomas are rare tumors of notochord remnants, occurring mainly in the sacrum and skull
base. Despite of their unusually slow growth, chordomas are highly invasive and the …
base. Despite of their unusually slow growth, chordomas are highly invasive and the …
Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific …
DNA methylation is a key epigenetic mark that is critical for gene regulation in multicellular
eukaryotes. Although various human cell types may have the same genome, these cells …
eukaryotes. Although various human cell types may have the same genome, these cells …
DNA methylation dynamics: identification and functional annotation
DNA methylation is an epigenetic modification of cytosines that undergoes dynamic
changes in a temporal, spatial and cell-type-specific manner. Recent advances in …
changes in a temporal, spatial and cell-type-specific manner. Recent advances in …
CD47 is a direct target of SNAI1 and ZEB1 and its blockade activates the phagocytosis of breast cancer cells undergoing EMT
MZ Noman, K Van Moer, V Marani, RM Gemmill… - …, 2018 - Taylor & Francis
We report that CD47 was upregulated in different EMT-activated human breast cancer cells
versus epithelial MCF7 cells. Overexpression of SNAI1 or ZEB1 in epithelial MCF7 cells …
versus epithelial MCF7 cells. Overexpression of SNAI1 or ZEB1 in epithelial MCF7 cells …
Multiple network algorithm for epigenetic modules via the integration of genome-wide DNA methylation and gene expression data
Background With the increase in the amount of DNA methylation and gene expression data,
the epigenetic mechanisms of cancers can be extensively investigate. Available methods …
the epigenetic mechanisms of cancers can be extensively investigate. Available methods …
Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers
Background DNA methylation is the major form of epigenetic modifications through which
the cell regulates the gene expression and silencing. There have been extensive studies on …
the cell regulates the gene expression and silencing. There have been extensive studies on …