The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

Virulence-associated enzymes of Cryptococcus neoformans

F Almeida, JM Wolf, A Casadevall - Eukaryotic cell, 2015 - Am Soc Microbiol
Enzymes play key roles in fungal pathogenesis. Manipulation of enzyme expression or
activity can significantly alter the infection process, and enzyme expression profiles can be a …

Immune recognition of fungal polysaccharides

BD Snarr, ST Qureshi, DC Sheppard - Journal of fungi, 2017 - mdpi.com
The incidence of fungal infections has dramatically increased in recent years, in large part
due to increased use of immunosuppressive medications, as well as aggressive medical …

Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts

CA Specht, CK Lee, H Huang, DJ Tipper, ZT Shen… - MBio, 2015 - Am Soc Microbiol
ABSTRACT A vaccine capable of protecting at-risk persons against infections due to
Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global …

The tools for virulence of Cryptococcus neoformans

C Coelho, AL Bocca, A Casadevall - Advances in applied microbiology, 2014 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …

Peeling the onion: the outer layers of Cryptococcus neoformans

DP Agustinho, LC Miller, LX Li… - Memórias do Instituto …, 2018 - SciELO Brasil
Cryptococcus neoformans is an opportunistic fungal pathogen that is ubiquitous in the
environment. It causes a deadly meningitis that is responsible for over 180,000 deaths …

Update on the epidemiology and management of cryptococcal meningitis

A Desalermos, TK Kourkoumpetis… - Expert opinion on …, 2012 - Taylor & Francis
Despite recent improvements in the diagnosis and treatment of cryptococcosis, cryptococcal
meningitis is responsible for> 600,000 deaths/year worldwide. The aim of this work is to …

Cryptococcus: History, Epidemiology and Immune Evasion

I Diniz-Lima, LM Fonseca, EB Silva-Junior… - Applied Sciences, 2022 - mdpi.com
Cryptococcosis is a disease caused by the pathogenic fungi Cryptococcus neoformans and
Cryptococcus gattii, both environmental fungi that cause severe pneumonia and may even …

Adhesins in the virulence of opportunistic fungal pathogens of human

A Kumari, AH Tripathi, P Gautam, R Gahtori, A Pande… - Mycology, 2021 - Taylor & Francis
Aspergillosis, candidiasis, and cryptococcosis are the most common cause of mycoses-
related disease and death among immune-compromised patients. Adhesins are cell-surface …

[HTML][HTML] The heat shock protein (Hsp) 70 of Cryptococcus neoformans is associated with the fungal cell surface and influences the interaction between yeast and host …

CP Silveira, AC Piffer, L Kmetzsch, FL Fonseca… - Fungal Genetics and …, 2013 - Elsevier
The pathogenic yeast Cryptococcus neoformans secretes numerous proteins, such as heat
shock proteins, by unconventional mechanisms during its interaction with host cells. Hsp70 …