Emerging biomedical tools for biomarkers detection and diagnostics in schistosomiasis

RRM Lima, JVA Lima, JFF Ribeiro, JB Nascimento… - Talanta, 2023 - Elsevier
Schistosomiasis is a neglected disease that strikes many people from tropical and
subtropical countries where there are not satisfactory sanitation and wide access to clean …

Diagnostic performances of Schistosoma haematobium and Schistosoma mansoni recombinant proteins, peptides and chimeric proteins antibody based tests …

A Vengesai, V Muleya, H Midzi, TV Tinago, I Chipako… - Plos one, 2023 - journals.plos.org
Background Traditional diagnostic tests for schistosome infections are suboptimal,
particularly when the parasite burden is low. In the present review we sought to identify …

Evaluation of copromicroscopy and serology to measure the exposure to Ascaris infections across age groups and to assess the impact of 3 years of biannual mass …

D Dana, J Vlaminck, M Ayana, B Tadege… - PLoS neglected …, 2020 - journals.plos.org
Background The scientific community has recently summarized the desired characteristics
for diagnostic tools across the different phases of a soil-transmitted helminth (STH) mass …

Plasmodium falciparum and helminth coinfections increase IgE and parasite-specific IgG responses

R Santano, R Rubio, B Grau-Pujol, V Escola… - Microbiology …, 2021 - Am Soc Microbiol
Coinfection with Plasmodium falciparum and helminths may impact the immune response to
these parasites because they induce different immune profiles. We studied the effects of …

Immunoblotting Identification of Diagnostic Antigens of Paragonimus westermani Type 1 for the Detection of Human Pulmonary Paragonimiasis in North East India

KR Devi, A Deka, D Mukherjee, H Kaur… - Tropical Medicine and …, 2023 - mdpi.com
Human pulmonary paragonimiasis, an emerging concern in North East India, frequently
masquerades as pulmonary tuberculosis due to clinical and radiological similarities, leading …

新型等温扩增技术推动寄生虫病现场快速检测能力提升

张逸龙, 潘卫庆 - 中国血吸虫病防治杂志, 2020 - zgxfzz.com
随着分子生物学的快速发展, 等温扩增技术凭借其高效, 快速和简便等优势,
现已开始应用于寄生虫病病原核酸检测, 并成为推进寄生虫病现场检测和防控工作的重要手段 …

Schistosome proteomics: updates and clinical implications

W Castro-Borges, RA Wilson - Expert Review of Proteomics, 2022 - Taylor & Francis
Introduction Schistosomes are long-lived blood dwelling helminth parasites using intricate
mechanisms to invade, mature, and reproduce inside their vertebrate hosts, whilst …

Evaluation of isotype-based serology for diagnosis of Schistosoma mansoni infection in individuals living in endemic areas with low parasite burden

F do Carmo Magalhães, JMP Moreira, MC de Rezende… - Acta Tropica, 2023 - Elsevier
Intestinal schistosomiasis is a chronic and debilitating disease that affects public health
systems worldwide. Control interventions to reduce morbidity primarily involve the diagnosis …

Evaluation of schistosomula crude antigen (SCA) as a diagnostic tool for Schistosoma mansoni in low endemic human population

OT Oyeyemi, CA Corsini, G Gonçalves… - Scientific Reports, 2021 - nature.com
The study aimed to determine the potential of schistosomula crude antigen (SCA) as a
diagnostic target for anti-S. mansoni antibody detection. Cercariae were transformed into …

Diagnostic tests for schistosomiasis for low prevalence settings: a systematic review and meta-analysis

MT Vaillant, F Philippy, J Barré, D Bulaev, AT Garba - medRxiv, 2021 - medrxiv.org
Background Tests for diagnosing schistosomiasis in areas where prevalence is low due to
control programme of the disease should be suffiently sensitive to detect the residual …