Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …

The need for new antibacterial drugs to treat the increasing global prevalence of drug-
resistant bacterial infections has clearly attracted global attention, with a range of existing …

Page 1 2021 ANTIBACTERIAL AGENTS IN CLINICAL AND PRECLINICAL DEVELOPMENT:
an overview and analysis World Health Organization Page 2 A PRE Page 3 2021 …

The sulfonamides (sulfas) are the oldest class of antibacterial drugs and inhibit the bacterial
dihydropteroate synthase (DHPS, encoded by folP), through chemical mimicry of its co …

Antimicrobial peptides (AMPs), or host defence peptides, are short proteins in various life
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …

Advances in areas that include genomics, systems biology, protein structure determination
and artificial intelligence provide new opportunities for target-based antibacterial drug …

Antimicrobial resistance (AMR) is a global threat to society due to the increasing emergence
of multi-drug resistant bacteria that are not susceptible to our last line of defence antibiotics …

The sensitive detection of bacterial infections is a prerequisite for their successful treatment.
The use of a chemiluminescent readout was so far hampered by an insufficient probe …

Surface‐enhanced Raman spectroscopy (SERS) has shown strength in non‐invasive, rapid,
trace analysis and has been used in many fields in medicine. Machine learning (ML) is an …