Pathologic mechanisms of the Newcastle disease virus

D Zhang, Z Ding, X Xu - Viruses, 2023 - mdpi.com
Newcastle disease (ND) has been a consistent risk factor to the poultry industry worldwide.
Its pathogen, Newcastle disease virus (NDV), is also a promising antitumor treatment …

Leonurine: from gynecologic medicine to pleiotropic agent

Y Li, Y Lin, X Liu, L Wang, M Yu, D Li, Y Zhu… - Chinese Journal of …, 2020 - Springer
Abstract Leonurus japonicus Houtt, a Chinese traditional herbal medicine, has been widely
used to cure gynecological diseases, such as incomplete abortion and menoxenia …

PI3K/AKT/p53 pathway inhibits infectious spleen and kidney necrosis virus infection by regulating autophagy and immune responses

X Zhang, Y Ming, X Fu, Y Niu, Q Lin, H Liang… - Fish & Shellfish …, 2022 - Elsevier
Abstract The PI3K/AKT/p53 signaling pathway is activated by various types of cellular stimuli
or pathogenic infection, and then regulates fundamental cellular functions to combat these …

Live and let die: signaling AKTivation and UPRegulation dynamics in SARS-CoVs infection and cancer

M Suaya, GM Sánchez, A Vila, A Amante… - Cell Death & …, 2022 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic. Of particular interest …

miR-638 Inhibits immature Sertoli cell growth by indirectly inactivating PI3K/AKT pathway via SPAG1 gene

P Hu, K Guan, Y Feng, C Ma, H Song, Y Li, X Xia, J Li… - Cell Cycle, 2017 - Taylor & Francis
Numerous studies have demonstrated that microRNAs (miRNAs) play important roles in cell
growth, apoptosis and spermatogenesis. Our previous study showed that miR-638 was …

Emerging translation strategies during virus–host interaction

HD Hoang, S Neault, A Pelin… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Translation control is crucial during virus–host interaction. On one hand, viruses completely
rely on the protein synthesis machinery of host cells to propagate and have evolved various …

Battling for ribosomes: translational control at the forefront of the antiviral response

HD Hoang, TE Graber, T Alain - Journal of molecular biology, 2018 - Elsevier
In the early stages of infection, gaining control of the cellular protein synthesis machinery
including its ribosomes is the ultimate combat objective for a virus. To successfully replicate …

Forsythoside A inhibits apoptosis and autophagy induced by infectious bronchitis virus through regulation of the PI3K/Akt/NF-κB pathway

J Xu, P Yin, X Liu, X Hou - Microbiology Spectrum, 2023 - Am Soc Microbiol
Infectious bronchitis virus (IBV) causes an acute and highly infectious viral disease of
chickens, which brings huge economic losses to the poultry industry. Forsythoside A (FTA) is …

Phosphatidylinositol-3-kinase-Akt pathway in negative-stranded RNA virus infection: a minireview

J Blanco, C Cameirao, MC López, I Muñoz-Barroso - Archives of Virology, 2020 - Springer
Abstract The PI3K/Akt signalling pathway is a crucial signalling cascade that regulates
transcription, protein translation, cell growth, proliferation, cell survival, and metabolism …

Ca2+‐dependent release of ATP from astrocytes affects herpes simplex virus type 1 infection of neurons

DD Li Puma, ME Marcocci, G Lazzarino, G De Chiara… - Glia, 2021 - Wiley Online Library
Astrocytes provide metabolic support for neurons and modulate their functions by releasing
a plethora of neuroactive molecules diffusing to neighboring cells. Here we report that …