To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis

M Giustiniano, A Basso, V Mercalli… - Chemical Society …, 2017 - pubs.rsc.org
The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

Controlled microwave heating in modern organic synthesis: highlights from the 2004–2008 literature

CO Kappe, D Dallinger - Molecular diversity, 2009 - Springer
Direct and rapid heating by microwave irradiation in combination with sealed vessel
processing in many cases enables reactions to be carried out in a fraction of the time …

[HTML][HTML] General and efficient Cu-catalyzed three component coupling reaction toward imidazoheterocycles: one-pot synthesis of alpidem and zolpidem

N Chernyak, V Gevorgyan - Angewandte Chemie (International ed …, 2010 - ncbi.nlm.nih.gov
Imidazopyridine is an important pharmacophore widely found in many biologically active
compounds.[i] Particularly, imidazo [1, 2-a] pyridine is an essential fragment present in …

Strecker reaction and α-amino nitriles: Recent advances in their chemistry, synthesis, and biological properties

VV Kouznetsov, CEP Galvis - Tetrahedron, 2018 - Elsevier
Abstract α-Amino nitrile compounds have a profound impact on bio-chemical sciences, as
they have been prepared from inexpensive starting materials and have become valuable …

Recent developments in the synthesis of imidazo [1, 2-a] pyridines

K Pericherla, P Kaswan, K Pandey, A Kumar - Synthesis, 2015 - thieme-connect.com
Advances in the last decade for the synthesis of the imidazo [1, 2-a] pyridine scaffold from
various substrates employing approaches such as multicomponent reactions, tandem …

Isocyanide based [4+ 1] cycloaddition reactions: an indispensable tool in multi-component reactions (MCRs)

T Kaur, P Wadhwa, S Bagchi, A Sharma - Chemical Communications, 2016 - pubs.rsc.org
The advent of cycloaddition reactions in the synthesis of heterocycles and their ever
burgeoning applications in the fields of material chemistry, catalysis and drugs have been a …

Diversity-oriented synthesis of fused-imidazole derivatives via Groebke–Blackburn–Bienayme reaction: a review

N Devi, RK Rawal, V Singh - Tetrahedron, 2015 - Elsevier
In recent time, diversity-oriented synthesis of small chemical entities has been emerged as a
possible tool for exploring the intersections between chemistry and biology. These small …

Cu(I)-Catalyzed Synthesis of Imidazo[1,2-a]pyridines from Aminopyridines and Nitroolefins Using Air as the Oxidant

RL Yan, H Yan, C Ma, ZY Ren, XA Gao… - The Journal of …, 2012 - ACS Publications
A copper-catalyzed method for the synthesis of imidazo [1, 2-a] pyridines with
aminopyridines and nitroolefins using air as oxidation agent in a one-pot procedure has …

A remote-controlled adaptive medchem lab: an innovative approach to enable drug discovery in the 21st Century

AG Godfrey, T Masquelin, H Hemmerle - Drug Discovery Today, 2013 - Elsevier
Highlights•An innovative highly integrated, automated, remote-controlled synthesis suite.•A
highly integrated automated solution-phase synthesis and purification solution.•A new …

Medicinal attributes of imidazo [1, 2-a] pyridine derivatives: an update

N Devi, D Singh, RK Rawal, J Bariwal… - Current topics in …, 2016 - ingentaconnect.com
The imidazo [1, 2-a] pyridine scaffold is recognized as a privileged structure as it represents
a promising area for identification of lead structures towards the discovery of new synthetic …