Background: Apolipoprotein E (apoE) genotypes play critical roles in lipid metabolism and
are believed to influence risk for coronary heart disease (CHD). Despite many population …

Background: Although men and women share most genetic information, they have
significantly different disease susceptibilities that go well beyond the expected gender …

Background: Serum lipid concentrations are modulated by environmental factors such as
exercise, alcohol intake, smoking, obesity and dietary intake and genetic factors …

Objective—The association of alcohol use with atherosclerosis is inconsistent in previous
studies. Methods and Results—For the Cardiovascular Health Study, 5888 adults aged 65 …

Given the higher burden of risk factors for metabolic syndrome (MetS) on morbidity and
mortality, it is critical to prevent the development of metabolic syndrome in the first place …

Objective: We sought to determine the relation of alcohol intake and systemic inflammation
in a population-based sample of older adults. Methods and results: As part of the …

Numerous studies have demonstrated that increased C‐reactive protein (CRP) levels
predict coronary heart disease, stroke, peripheral vascular disease, and diabetes, and are …

Apolipoprotein E (ApoE) is a major constituent of many lipoprotein particles. Previous
genetic studies have focused on six genotypes defined by three alleles, denoted ε2, ε3, and …

Background Conflicting evidence exists on whether smoking acts as an effect modifier of the
association between APOE genotype and risk of coronary heart disease (CHD). Methods …

The purpose of this study was to describe the falls that occurred over a 5-year period in a
group of older adults living in a continuing care retirement community (CCRC) and to test …