Myelin-oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a recently
identified autoimmune disorder that presents in both adults and children as CNS …

Anti-myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-Abs) were first detected
by immunoblot and enzyme-linked immunosorbent assay nearly 30 years ago, but their …

Active multiple sclerosis lesions show inflammatory changes suggestive of a combined
attack by autoreactive T and B lymphocytes against brain white matter. These pathogenic …

Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
(CNS) leading to the progressive destruction of the myelin sheath surrounding axons. It can …

Myelin oligodendrocyte glycoprotein (MOG), a member of the immunoglobulin (Ig)
superfamily, is a myelin protein solely expressed at the outermost surface of myelin sheaths …

We describe new T cell receptor (TCR) transgenic mice (relapsing-remitting [RR] mice)
carrying a TCR specific for myelin oligodendrocyte glycoprotein (MOG) peptide 92–106 in …

We describe a double-transgenic mouse strain (o ptico s pinal E AE [OSE] mouse) that
spontaneously develops an EAE-like neurological syndrome closely resembling a human …

Butyrophilin molecules (commonly contracted to BTN), collectively take their name from the
eponymous protein in cow's milk. They are considered to be members of the B7 family of …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by formation of
amyloid‐β (Aβ) plaques, activated microglia, and neuronal cell death leading to progressive …

Multiple sclerosis (MS) is an inflammatory and demyelinating condition of the CNS,
characterized by perivascular infiltrates composed largely of T lymphocytes and …