The rat possesses hemochorial placentation with deep intrauterine trophoblast cell invasion
and trophoblast-directed uterine spiral artery remodeling; features shared with human …

Harkness and Wagner's Biology and Medicine of Rabbits and Rodents, Fifth Edition is a
practical reference in small mammal husbandry and health, encompassing the fields of …

Rodent models have opened the door to a better understanding of the neurobiology of brain
disorders and increased our ability to evaluate novel treatments. Resting-state functional …

Interferon regulatory factor 1 (IRF1), a critical member of the IRF family, was previously
shown to be associated with the immune system and to be involved in apoptosis and tumor …

Abstract The Rat Genome Database (RGD,) is one of the core resources for rat genomics
and recent developments have focused on providing support for disease-based research …

Background Digital gene expression (DGE) profiling has become an established tool to
study RNA expression. Here, we provide an in-depth analysis of small RNA DGE profiles …

The conservative nature of animal evolution makes animal models the ideal tool for learning
about human biology. The Handbook of Laboratory Animal Science, Second Edition: Animal …

The objective of this study was to determine the effects of various physical interventions such
as centrifugation regimes, Percoll gradient separation, and repeated pipetting on various …

The rat has served as an excellent model for studies on animal physiology and as a model
for human diseases such as diabetes and alcoholism; however, genetic studies have been …

Osmotic stress is an important factor that can result in cell damage during cryopreservation.
The objectives of this study were to determine:(1) isosmotic sperm cell volume;(2) …