“Autoinflammatory psoriasis”—genetics and biology of pustular psoriasis

R Uppala, LC Tsoi, PW Harms, B Wang… - Cellular & molecular …, 2021 - nature.com
Psoriasis is a chronic inflammatory skin condition that has a fairly wide range of clinical
presentations. Plaque psoriasis, which is the most common manifestation of psoriasis, is …

Anti-interleukin and interleukin therapies for psoriasis: current evidence and clinical usefulness

YC Tsai, TF Tsai - Therapeutic advances in musculoskeletal …, 2017 - journals.sagepub.com
Anti-interleukin (IL) therapies have emerged as a major treatment for patients with moderate-
to-severe psoriasis. This article reviews the up-to-date results of pivotal clinical trials …

Estradiol suppresses psoriatic inflammation in mice by regulating neutrophil and macrophage functions

A Adachi, T Honda, G Egawa, S Kanameishi… - Journal of Allergy and …, 2022 - Elsevier
Background Psoriasis is a common inflammatory skin disease resulting from dysregulation
of the IL-23/TH 17 immune axis. The prevalence and severity of psoriasis is higher in men …

Are neutrophilic dermatoses autoinflammatory disorders?

TK Satoh, M Mellett, E Contassot… - British Journal of …, 2018 - academic.oup.com
Neutrophils constitute essential players in inflammatory responses and are the first line of
defence against harmful stimuli. However, dysregulation of neutrophil homeostasis can …

What do we know about palmoplantar pustulosis?

M Misiak‐Galazka, H Wolska… - Journal of the European …, 2017 - Wiley Online Library
Palmoplantar pustulosis is characterized by a chronic eruption of sterile pustules on palms
and soles. The disease affects mainly women in the sixth and seventh decade of life. Some …

Palmoplantar psoriasis

B Engin, Ö Aşkın, Y Tüzün - Clinics in dermatology, 2017 - Elsevier
Palmoplantar psoriasis refers to a localized psoriasis variant. The disease can be
associated with many clinical forms, including predominantly pustular lesions to thick scaly …

IL-1 family cytokines in inflammatory dermatoses: pathogenetic role and potential therapeutic implications

H Iznardo, L Puig - International Journal of Molecular Sciences, 2022 - mdpi.com
The interleukin-1 (IL-1) family is involved in the correct functioning and regulation of the
innate immune system, linking innate and adaptative immune responses. This complex …

Current therapeutic overview and future perspectives regarding the treatment of psoriasis

F Ferrara, C Verduci, E Laconi, A Mangione… - International …, 2024 - Elsevier
Psoriasis is a chronic inflammatory skin disease affecting millions of people worldwide,
characterized by rapid proliferation of keratinocytes, immune cell infiltration, and systemic …

[HTML][HTML] Therapeutic advances in psoriasis: from biologics to emerging oral small molecules

F Ferrara, C Verduci, E Laconi, A Mangione, C Dondi… - Antibodies, 2024 - mdpi.com
Psoriasis is a persistent, inflammatory condition affecting millions globally, marked by
excessive keratinocyte proliferation, immune cell infiltration, and widespread inflammation …

Review of treatments for generalized pustular psoriasis

DG Kearns, VS Chat, PD Zang, G Han… - Journal of …, 2021 - Taylor & Francis
Background Generalized pustular psoriasis (GPP) is an uncommon variant of psoriasis that
is characterized clinically by sterile pustule formation superimposed over inflamed …