Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease

L Castera, M Friedrich-Rust, R Loomba - Gastroenterology, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …

Apoptosis and necroptosis in the liver: a matter of life and death

RF Schwabe, T Luedde - Nature reviews Gastroenterology & …, 2018 - nature.com
Cell death represents a basic biological paradigm that governs outcomes and long-term
sequelae in almost every hepatic disease condition. Acute liver failure is characterized by …

Noninvasive biomarkers in NAFLD and NASH—current progress and future promise

VWS Wong, LA Adams, V de Lédinghen… - Nature reviews …, 2018 - nature.com
Nonalcoholic fatty liver disease (NAFLD) affects 25% of the global adult population and is
the most common chronic liver disease worldwide. Nonalcoholic steatohepatitis (NASH) is …

Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers

E Vilar-Gomez, N Chalasani - Journal of hepatology, 2018 - Elsevier
The correct identification of patients at increased risk of non-alcoholic steatohepatitis
(NASH) and advanced fibrosis is a critical step in the assessment of non-alcoholic fatty liver …

High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms

CY Lian, ZZ Zhai, ZF Li, L Wang - Chemico-biological interactions, 2020 - Elsevier
Obesity is characterized by the deposition of excessive body fat, and is caused by energy
imbalance, especially when consuming fat-rich diets. High fat diet (HFD)-associated obesity …

Nonalcoholic fatty liver disease: a systematic review

ME Rinella - Jama, 2015 - jamanetwork.com
Importance Nonalcoholic fatty liver disease and its subtype nonalcoholic steatohepatitis
affect approximately 30% and 5%, respectively, of the US population. In patients with …

Asia–Pacific Working Party on Non‐alcoholic Fatty Liver Disease guidelines 2017—part 1: definition, risk factors and assessment

VWS Wong, WK Chan, S Chitturi… - Journal of …, 2018 - Wiley Online Library
Since the publication of the guidelines for the assessment and management of non alcoholic
fatty liver disease (NAFLD) by the Asia–Pacific Working Party on NAFLD in 2007, 1 our …

Non-alcoholic fatty liver disease: a practical approach to diagnosis and staging

JK Dyson, QM Anstee, S McPherson - Frontline gastroenterology, 2014 - fg.bmj.com
Non-alcoholic fatty liver disease (NAFLD) is now the commonest cause of abnormal liver
function tests (LFTs) in the UK with approximately a third of the population being affected …

Clinical and molecular biomarkers for diagnosis and staging of NAFLD

S Di Mauro, A Scamporrino, A Filippello… - International journal of …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common hepatic pathology in
industrialized countries, affecting about 25% of the general population. NAFLD is a benign …

Diagnosis of non-alcoholic fatty liver disease (NAFLD): current concepts

M Papatheodoridi, E Cholongitas - Current pharmaceutical …, 2018 - ingentaconnect.com
Nonalcoholic fatty liver disease (NAFLD) ranges from simple hepatic steatosis to non-
alcoholic steatohepatitis (NASH) and cirrhosis. The majority of NAFLD patients do not …