[HTML][HTML] Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast …

HJ Burstein, G Curigliano, B Thürlimann, WP Weber… - Annals of oncology, 2021 - Elsevier
The 17th St Gallen International Breast Cancer Consensus Conference in 2021 was held
virtually, owing to the global COVID-19 pandemic. More than 3300 participants took part in …

Breast cancer—epidemiology, classification, pathogenesis and treatment (review of literature)

B Smolarz, AZ Nowak, H Romanowicz - Cancers, 2022 - mdpi.com
Simple Summary Breast cancer is the most-commonly diagnosed malignant tumor in women
in the world, as well as the first cause of death from malignant tumors. The incidence of …

[HTML][HTML] Event-free survival with pembrolizumab in early triple-negative breast cancer

P Schmid, J Cortes, R Dent, L Pusztai… - … England Journal of …, 2022 - Mass Medical Soc
Background The addition of pembrolizumab to neoadjuvant chemotherapy led to a
significantly higher percentage of patients with early triple-negative breast cancer having a …

Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with …

EA Mittendorf, H Zhang, CH Barrios, S Saji, KH Jung… - The Lancet, 2020 - thelancet.com
Background Preferred neoadjuvant regimens for early-stage triple-negative breast cancer
(TNBC) include anthracycline-cyclophosphamide and taxane-based chemotherapy …

[HTML][HTML] Adjuvant and neoadjuvant breast cancer treatments: A systematic review of their effects on mortality

AJ Kerr, D Dodwell, P McGale, F Holt, F Duane… - Cancer treatment …, 2022 - Elsevier
Background Adjuvant and neoadjuvant breast cancer treatments can reduce breast cancer
mortality but may increase mortality from other causes. Information regarding treatment …

[HTML][HTML] Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer

ANJ Tutt, JE Garber, B Kaufman, G Viale… - … England Journal of …, 2021 - Mass Medical Soc
Background Poly (adenosine diphosphate–ribose) polymerase inhibitors target cancers with
defects in homologous recombination repair by synthetic lethality. New therapies are …

[HTML][HTML] Pembrolizumab for early triple-negative breast cancer

P Schmid, J Cortes, L Pusztai, H McArthur… - … England Journal of …, 2020 - Mass Medical Soc
Background Previous trials showed promising antitumor activity and an acceptable safety
profile associated with pembrolizumab in patients with early triple-negative breast cancer …

[PDF][PDF] Breast Cancer: Updated and Deep Insights

KM Cuthrell, N Tzenios - International Research Journal of …, 2023 - researchgate.net
Breast cancer is the most common cancer diagnosed in females throughout the entire world,
and it is also the primary reason why people lose their lives due to malignant tumors. The …

[HTML][HTML] Duration of adjuvant aromatase-inhibitor therapy in postmenopausal breast cancer

M Gnant, F Fitzal, G Rinnerthaler… - … England Journal of …, 2021 - Mass Medical Soc
Background For postmenopausal women with hormone-receptor–positive breast cancer, the
most effective duration for adjuvant therapy with an aromatase inhibitor remains unclear …

Immune infiltrates in breast cancer: recent updates and clinical implications

MV Dieci, F Miglietta, V Guarneri - Cells, 2021 - mdpi.com
In recent decades, the increasing interest in the field of immunotherapy has fostered an
intense investigation of the breast cancer (BC) immune microenvironment. In this context …