Zinc signals and immunity
M Maywald, I Wessels, L Rink - International journal of molecular sciences, 2017 - mdpi.com
Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency
as well as zinc excess result in severe disturbances in immune cell numbers and activities …
as well as zinc excess result in severe disturbances in immune cell numbers and activities …
[HTML][HTML] The molecular basis of mammary gland development and epithelial differentiation
PF Slepicka, AVH Somasundara… - Seminars in cell & …, 2021 - Elsevier
Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …
organ systems has been increasing rapidly in recent years. With the advent of new and …
Biological underpinnings of breastfeeding challenges: the role of genetics, diet, and environment on lactation physiology
S Lee, SL Kelleher - American Journal of Physiology …, 2016 - journals.physiology.org
Lactation is a dynamic process that has evolved to produce a complex biological fluid that
provides nutritive and nonnutritive factors to the nursing offspring. It has long been assumed …
provides nutritive and nonnutritive factors to the nursing offspring. It has long been assumed …
ROS and intracellular ion channels
K Kiselyov, S Muallem - Cell Calcium, 2016 - Elsevier
Oxidative stress is a well-known driver of numerous pathological processes involving protein
and lipid peroxidation and DNA damage. The resulting increase of pro-apoptotic pressure …
and lipid peroxidation and DNA damage. The resulting increase of pro-apoptotic pressure …
[HTML][HTML] Molecular mechanism of mammary gland involution: An update
MK Jena, S Jaswal, S Kumar, AK Mohanty - Developmental biology, 2019 - Elsevier
The mammary gland (MG) is a unique organ responsible for milk synthesis, secretion, and
involution to prepare the gland for subsequent lactation. The mammary epithelial cells …
involution to prepare the gland for subsequent lactation. The mammary epithelial cells …
How cellular Zn2+ signaling drives physiological functions
N Levaot, M Hershfinkel - Cell Calcium, 2018 - Elsevier
Zinc is an essential micronutrient affecting many aspects of human health. Cellular Zn 2+
homeostasis is critical for cell function and survival. Zn 2+, acting as a first or second …
homeostasis is critical for cell function and survival. Zn 2+, acting as a first or second …
Breast cancers co-opt normal mechanisms of tolerance to promote immune evasion and metastasis
Normal developmental processes, such as those seen during embryonic development and
postpartum mammary gland involution, can be reactivated by cancer cells to promote …
postpartum mammary gland involution, can be reactivated by cancer cells to promote …
The role of lysosome in cell death regulation
F Yu, Z Chen, B Wang, Z Jin, Y Hou, S Ma, X Liu - Tumor Biology, 2016 - Springer
Lysosome is a highly membrane-bound organelle which possesses a sequence of
biological functions including protein degradation, cell signal transduction, plasma …
biological functions including protein degradation, cell signal transduction, plasma …
Virulence‐associated protein A from Rhodococcus equi is an intercompartmental pH‐neutralising virulence factor
K Von Bargen, M Scraba, I Krämer… - Cellular …, 2019 - Wiley Online Library
Professional phagocytic cells such as macrophages are a central part of innate immune
defence. They ingest microorganisms into membrane‐bound compartments (phagosomes) …
defence. They ingest microorganisms into membrane‐bound compartments (phagosomes) …
ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion
Y Golan, R Alhadeff, A Warshel… - PLOS Computational …, 2019 - journals.plos.org
Zinc is a vital trace element crucial for the proper function of some 3,000 cellular proteins.
Specifically, zinc is essential for key physiological processes including nucleic acid …
Specifically, zinc is essential for key physiological processes including nucleic acid …