Prevention and treatment of papillomavirus-related cancers through immunization

IH Frazer, GR Leggatt… - Annual review of …, 2011 - annualreviews.org
Cervical and other anogenital cancers are initiated by infection with one of a small group of
human papillomaviruses (HPV). Virus-like particle-based vaccines have recently been …

HPV pathogenesis, various types of vaccines, safety concern, prophylactic and therapeutic applications to control cervical cancer, and future perspective

S Ashique, A Hussain, N Fatima, MA Altamimi - VirusDisease, 2023 - Springer
Over 98% of cervical cancers (CC) are caused by regular infections with" high risk" genotype
of the human papilloma virus (HPV). However, this is not always the causative factor …

Prime-boost vaccination strategy in women with high-grade, noncervical anogenital intraepithelial neoplasia: clinical results from a multicenter phase II trial

AN Fiander, AJ Tristram, EJ Davidson… - International Journal of …, 2006 - ijgc.bmj.com
The objective of this study was to determine the clinical effectiveness of a prime-boost
human papillomavirus (HPV) vaccine regimen. A nonrandomized phase II prime-boost …

Design, immune responses and anti-tumor potential of an HPV16 E6E7 multi-epitope vaccine

LMF de Oliveira, MG Morale, AAM Chaves… - Plos one, 2015 - journals.plos.org
Cervical cancer is a common type of cancer among women worldwide and infection with
high-risk human papillomavirus (HPVs) types represents the major risk factor for the …

T-cell responses to human papillomavirus type 16 among women with different grades of cervical neoplasia

JC Steele, CH Mann, S Rookes, T Rollason… - British journal of …, 2005 - nature.com
Infection with high-risk genital human papillomavirus (HPV) types is a major risk factor for
the development of cervical intraepithelial neoplasia (CIN) and invasive cervical carcinoma …

Expression of CD200 on AML blasts directly suppresses memory T-cell function

SJ Coles, RK Hills, ECY Wang, AK Burnett, S Man… - Leukemia, 2012 - nature.com
Previous studies have shown that immunosuppression in acute myeloid leukemia (AML) is
associated with changes in the adaptive immune compartment. Such changes include the …

CD8+T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden

O Goodyear, K Piper, N Khan, J Starczynski… - Blood, 2005 - ashpublications.org
The expression of cancer germline antigens (CGAgs) is normally restricted to the testis but is
also present in many types of malignant cells including plasma cells from patients with …

Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors

CY Wu, LH Yang, HY Yang, J Knoff, S Peng… - Clinical Cancer …, 2014 - AACR
Purpose: Radiotherapy kills cancer cells by causing DNA damage, and stimulates a
systemic antitumor immune response by releasing tumor antigen and endogenous adjuvant …

Clinical responses to Cidofovir applied topically to women with high grade vulval intraepithelial neoplasia

A Tristram, A Fiander - Gynecologic oncology, 2005 - Elsevier
OBJECTIVES.: Cidofovir is an acyclic nucleoside phosphonate, with broad spectrum anti-
viral activity. It has previously been used in a number of clinical settings, including high …

Human papillomavirus vaccine: State of the art and future perspectives

D Panatto, D Amicizia, NL Bragazzi, E Rizzitelli… - Advances in protein …, 2015 - Elsevier
Human Papillomavirus (HPV) is a widely distributed and common virus, that causes benign
lesions (such as warts and papillomas) but, if not cleared, can lead to malignant lesions as …