Diagnosis and management of eosinophilic asthma: a US perspective

HH Walford, TA Doherty - Journal of asthma and allergy, 2014 - Taylor & Francis
Eosinophilic asthma is now recognized as an important subphenotype of asthma based on
the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be …

Lung dendritic cells at the innate-adaptive immune interface

TV Condon, RT Sawyer, MJ Fenton… - Journal of leukocyte …, 2011 - academic.oup.com
This review updates the basic biology of lung DCs and their functions. Lung DCs have taken
center stage as cellular therapeutic targets in new vaccine strategies for the treatment of …

Advances in mechanisms of asthma, allergy, and immunology in 2010

DH Broide, F Finkelman, BS Bochner… - Journal of Allergy and …, 2011 - Elsevier
2010 was marked by rapid progress in our understanding of the cellular and molecular
mechanisms involved in the pathogenesis of allergic inflammation and asthma. Studies …

Targeting IgE in asthma

K Kuhl, NA Hanania - Current opinion in pulmonary medicine, 2012 - journals.lww.com
Targeting IgE in asthma : Current Opinion in Pulmonary Medicine Targeting IgE in asthma :
Current Opinion in Pulmonary Medicine Log in or Register Subscribe to journalSubscribe Get …

Indoor-air purification by photoelectrochemical oxidation mitigates allergic airway responses to aerosolized cat dander in a murine model

D Devadoss, K Surbaugh, M Manevski… - Scientific Reports, 2023 - nature.com
Portable air purifiers help improve indoor air quality by neutralizing allergens, including
animal dander proteins. However, there are limited in-vivo models to assess the efficacy of …

Atopy and the gastrointestinal tract–a review of a common association in unexplained gastrointestinal disease

MM Walker, N Powell, NJ Talley - Expert review of …, 2014 - Taylor & Francis
In addition to diseases conventionally associated with atopy there is increasing recognition
that atopy is also linked to a spectrum of gastrointestinal (GI) manifestations, including food …

The importance of eosinophil, platelet and dendritic cell in asthma

SS Athari, SM Athari - Asian Pacific Journal of Tropical Disease, 2014 - Elsevier
Asthma is a syndrome of variable airflow obstruction. It is characterized pathologically by
bronchial inflammation and remodeling changes. Eosinophil infiltrate in asthma and a …

Omalizumab may decrease the thickness of the reticular basement membrane and fibronectin deposit in the bronchial mucosa of severe allergic asthmatics

W Zastrzeżyńska, M Przybyszowski… - Journal of …, 2020 - Taylor & Francis
Introduction: Immunoglobulin E is an important modulator of the inflammatory reaction in
allergic asthma. It also contributes to airway remodeling in the course of the disease. The …

Clinical effects and immune modulation of biologics in asthma

N Harada, J Ito, K Takahashi - Respiratory Investigation, 2021 - Elsevier
Asthma is considered a syndrome composed of heterogeneous disorders involving complex
chronic airway inflammation. Patients with severe asthma, prolonged symptoms, and …

Coexpression of type 2 immune targets in sputum-derived epithelial and dendritic cells from asthmatic subjects

B Bleck, A Kazeros, K Bakal, L Garcia-Medina… - Journal of Allergy and …, 2015 - Elsevier
Background Noninvasive sputum sampling has enabled the identification of biomarkers in
asthmatic patients. Studies of discrete cell populations in sputum can enhance …