The advent of affordable and rapid next-generation DNA sequencing technology, along with
the US Supreme Court ruling invalidating gene patents, has led to a deluge of germline and …

Radiotherapy remains an important treatment modality in nearly two thirds of all cancers,
including the primary curative or palliative treatment of breast cancer. Unfortunately, largely …

PURPOSE Standard curative-intent chemoradiotherapy for human papillomavirus (HPV)–
related oropharyngeal carcinoma results in significant toxicity. Since hypoxic tumors are …

Purpose: Molecular properties associated with complete response or acquired resistance to
concurrent chemotherapy and radiotherapy (CRT) are incompletely characterized …

Purpose: There is an urgent need for biomarkers of radiation response in organ-sparing
therapies. Bladder preservation with trimodality therapy (TMT), consisting of transurethral …

Purpose This study aims to combine multiparametric magnetic resonance imaging (MRI)
and digitized pathology with machine learning to generate predictive maps of histologic …

In the era of precision medicine, radiation medicine is currently focused on the precise
delivery of highly conformal radiation treatments. However, the tremendous developments in …

The effects of various forms of ionising radiation are known to be mediated by interactions
with cellular and molecular targets in irradiated and in some cases non-targeted tissue …

Due to the rapid increase in the availability of patient data, there is significant interest in
precision medicine that could facilitate the development of a personalized treatment plan for …

Objective: The Pediatric Proton/Photon Consortium Registry (PPCR) is a comprehensive
data registry composed of pediatric patients treated with radiation. It was established to …