[HTML][HTML] Phage therapy: From biological mechanisms to future directions
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …
the natural predators of bacteria discovered over 100 years ago. In order to use phages …
Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …
Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease
RM Dedrick, BE Smith, M Cristinziano… - Clinical infectious …, 2023 - academic.oup.com
Abstract Background Nontuberculous Mycobacterium infections, particularly Mycobacterium
abscessus, are increasingly common among patients with cystic fibrosis and chronic …
abscessus, are increasingly common among patients with cystic fibrosis and chronic …
[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies
D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …
use and residues of antibiotics in humans, animals, and the environment can exert selective …
Bacterial persisters: molecular mechanisms and therapeutic development
H Niu, J Gu, Y Zhang - Signal transduction and targeted therapy, 2024 - nature.com
Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
bacteria that survive in stress environments such as antibiotic exposure, acidic and …
Novel antimicrobial agents for combating antibiotic-resistant bacteria
Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …
Translating phage therapy into the clinic: Recent accomplishments but continuing challenges
A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …
Alternative therapeutic strategies to treat antibiotic-resistant pathogens
CR MacNair, ST Rutherford, MW Tan - Nature Reviews Microbiology, 2024 - nature.com
Resistance threatens to render antibiotics—which are essential for modern medicine—
ineffective, thus posing a threat to human health. The discovery of novel classes of …
ineffective, thus posing a threat to human health. The discovery of novel classes of …
Biomimetic Bacteriophage‐Like Particles Formed from Probiotic Extracts and NO Donors for Eradicating Multidrug‐Resistant Staphylococcus aureus
C Gong, W Guan, X Liu, Y Zheng, Z Li… - Advanced …, 2022 - Wiley Online Library
Effectively clearing multidrug‐resistant bacteria through nonantibiotic treatments is crucial
for the recovery of infected tissues in favorable biological environments. Herein, a thermally …
for the recovery of infected tissues in favorable biological environments. Herein, a thermally …
Understanding bacteriophage tail fiber interaction with host surface receptor: the key “blueprint” for reprogramming phage host range
Bacteriophages (phages), as natural antibacterial agents, are being rediscovered because
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …