MicroRNAs (miRNAs) are small, non-coding RNAs that post-transcriptionally regulate gene
expression by binding to specific mRNA targets and promoting their degradation and/or …

Liver cancer is the fourth leading cause of cancer deaths globally, of which hepatocellular
carcinoma (HCC) is the major subtype. Viral hepatitis B and C infections, alcohol abuse, and …

Ferroptosis is a recently recognized form of regulated cell death that is characterized by lipid
peroxidation. However, the molecular mechanisms regulating ferroptosis are largely …

Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

MicroRNAs (miRNAs) are small non-coding RNAs that regulate multiple physiological and
pathological functions through the modulation of gene expression at the post-transcriptional …

The collagen family contains 28 proteins, predominantly expressed in the extracellular
matrix (ECM) and characterized by a triple-helix structure. Collagens undergo several …

Pancreatic ductal adenocarcinoma (PDAC) lethality is due to metastatic dissemination.
Characterization of rare, heterogeneous circulating tumor cells (CTCs) can provide insight …

The excessive accumulation of extracellular matrix (ECM) is a key feature of liver fibrosis
and the activated hepatic stellate cells (HSCs) are the major producer of ECM proteins …

Hepatic stellate cell (HSC), initially analyzed by von Kupffer, in 1876, revealed to be an
extraordinary mesenchymal cell, essential for both hepatocellular function and lesions …

Cholangiopathies are diseases that affect cholangiocytes, the cells lining the biliary tract.
Liver stem cells (LSCs) are able to differentiate into all cells of the liver and possibly …