The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …

Cell transplantation therapy holds potential for repair and functional plasticity following
spinal cord injury (SCI). Stem and progenitor cells are capable of modifying the lesion …

Spinal cord injury (SCI) is a devastating condition that causes substantial morbidity and
mortality and for which no treatments are available. Stem cells offer some promise in the …

Objective: We sought to assess the safety and therapeutic efficacy of autologous human
bone marrow derived mononuclear cell transplantation on spinal cord injury in a phase I/II …

Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Introduction: Spinal cord injury (SCI) is a devastating condition, where regenerative failure
and cell loss lead to paralysis. The heterogeneous and time-sensitive pathophysiology has …

In the early 1980s experiments on spinalized cats showed that exercise training on the
treadmill could enhance locomotor recovery after spinal cord injury (SCI). In this review, we …

Rehabilitative motor training is currently one of the most widely used approaches to promote
moderate recovery following injuries of the central nervous system. Such training is …

Stem cell medicine has led to functional recovery in the acute-to-subacute phase of spinal
cord injury (SCI), but not yet in the chronic phase, during which various molecular …

Background Spinal cord injury (SCI) is a serious neurological spinal cord damage that
resulted in the loss of temporary or permanent function. However, there are even now no …