Integrating multi-omics data with EHR for precision medicine using advanced artificial intelligence

L Tong, W Shi, M Isgut, Y Zhong, P Lais… - IEEE Reviews in …, 2023 - ieeexplore.ieee.org
With the recent advancement of novel biomedical technologies such as high-throughput
sequencing and wearable devices, multi-modal biomedical data ranging from multi-omics …

Missing data matter: an empirical evaluation of the impacts of missing EHR data in comparative effectiveness research

Y Zhou, J Shi, R Stein, X Liu… - Journal of the …, 2023 - academic.oup.com
Objectives The impacts of missing data in comparative effectiveness research (CER) using
electronic health records (EHRs) may vary depending on the type and pattern of missing …

A novel method leveraging time series data to improve subphenotyping and application in critically ill patients with COVID-19

W Oh, P Jayaraman, P Tandon, US Chaddha… - Artificial Intelligence in …, 2024 - Elsevier
Computational subphenotyping, a data-driven approach to understanding disease subtypes,
is a prominent topic in medical research. Numerous ongoing studies are dedicated to …

[HTML][HTML] MixEHR-SurG: a joint proportional hazard and guided topic model for inferring mortality-associated topics from electronic health records

Y Li, AY Yang, A Marelli, Y Li - Journal of Biomedical Informatics, 2024 - Elsevier
Survival models can help medical practitioners to evaluate the prognostic importance of
clinical variables to patient outcomes such as mortality or hospital readmission and …

Using sequence clustering to identify clinically relevant subphenotypes in patients with COVID-19 admitted to the intensive care unit

W Oh, P Jayaraman, AS Sawant, L Chan… - Journal of the …, 2022 - academic.oup.com
Objective The novel coronavirus disease 2019 (COVID-19) has heterogenous clinical
courses, indicating that there might be distinct subphenotypes in critically ill patients …

Enhancing patient representation learning from electronic health records through predicted family relations

X Huang, J Arora, AM Erzurumluoglu, D Lam… - medRxiv, 2024 - medrxiv.org
Artificial intelligence and machine learning are powerful tools in analyzing electronic health
records (EHRs) for healthcare research. Despite the recognized importance of family health …

[HTML][HTML] DETECT: Feature extraction method for disease trajectory modeling in electronic health records

P Singhal, L Guare, C Morse, A Lucas… - AMIA Summits on …, 2023 - ncbi.nlm.nih.gov
Modeling with longitudinal electronic health record (EHR) data proves challenging given the
high dimensionality, redundancy, and noise captured in EHR. In order to improve precision …

DETECT: Feature extraction method for disease trajectory modeling

P Singhal, L Guare, C Morse, M Byrska-Bishop… - medRxiv, 2022 - medrxiv.org
Modeling with longitudinal electronic health record (EHR) data proves challenging given the
high dimensionality, redundancy, and noise captured in EHR. In order to improve precision …