Preferential binding of human BRCA1 protein with open X-like conformation of Holliday junction, a homologous recombination intermediate

SH Kabir, VK, N Pal - bioRxiv, 2024 - biorxiv.org
BRCA1 is a complex tumor suppressor protein involved in multiple critical cellular
processes, eg, DNA double strand break repair, cell cycle checkpoint, etc. BRCA1 depleted …