Multifunctional fructose 1, 6-bisphosphate aldolase as a therapeutic target

DB Pirovich, AA Da'dara, PJ Skelly - Frontiers in molecular …, 2021 - frontiersin.org
Fructose 1, 6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the
fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and …

Schistosome immunomodulators

S Acharya, AA Da'dara, PJ Skelly - PLoS Pathogens, 2021 - journals.plos.org
Schistosomes are long lived, intravascular parasitic platyhelminths that infect> 200 million
people globally. The molecular mechanisms used by these blood flukes to dampen host …

Fifty years of the schistosome tegument: discoveries, controversies, and outstanding questions

RA Wilson, MK Jones - International Journal for Parasitology, 2021 - Elsevier
The unique multilaminate appearance of the tegument surface of schistosomes was first
described in 1973, in one of the earliest volumes of the International Journal for …

Behind enemy lines: immunomodulatory armamentarium of the schistosome parasite

JMM Angeles, VJP Mercado, PT Rivera - Frontiers in Immunology, 2020 - frontiersin.org
The deeply rooted, intricate relationship between the Schistosoma parasite and the human
host has enabled the parasite to successfully survive within the host and surreptitiously …

Assessment of reference genes at six different developmental stages of Schistosoma mansoni for quantitative RT-PCR

GO Silveira, MS Amaral, HS Coelho, LF Maciel… - Scientific reports, 2021 - nature.com
Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is the
most used, fast, and reproducible method to confirm large-scale gene expression data. The …

Molecular characterization of glyceraldehyde-3-phosphate dehydrogenase from Eimeria tenella

W Huang, S Zhu, T Chen, Q Zhao, H Dong… - Parasitology …, 2022 - Springer
Chicken coccidiosis is an extremely common and lethally epidemic disease caused by
Eimeria spp. The control measures of coccidiosis depend mainly on drugs. However, the …

Proteomic analysis of Taenia solium cysticercus and adult stages

L Li, W He, X Fan, M Liu, B Luo, F Yang… - Frontiers in Veterinary …, 2023 - frontiersin.org
Taenia solium (T. solium) cysticercosis is a neglected parasitic zoonosis that occurs in
developing countries. Since T. solium has a complex life cycle that includes eggs …

A comprehensive and critical overview of schistosomiasis vaccine candidates

A Al-Naseri, S Al-Absi, R El Ridi, N Mahana - Journal of Parasitic Diseases, 2021 - Springer
A digenetic platyhelminth Schistosoma is the causative agent of schistosomiasis, one of the
neglected tropical diseases that affect humans and animals in numerous countries in the …

[HTML][HTML] Schistosoma mansoni phosphoglycerate mutase: a glycolytic ectoenzyme with thrombolytic potential

DB Pirovich, AA Da'dara, PJ Skelly - Parasite, 2022 - ncbi.nlm.nih.gov
Schistosomiasis is a debilitating parasitic disease caused by intravascular flatworms called
schistosomes (blood flukes) that affects> 200 million people worldwide. Proteomic analysis …

Transmission-Blocking Vaccines against Schistosomiasis Japonica

CP Zumuk, MK Jones, S Navarro, DJ Gray… - International Journal of …, 2024 - mdpi.com
Control of schistosomiasis japonica, endemic in Asia, including the Philippines, China, and
Indonesia, is extremely challenging. Schistosoma japonicum is a highly pathogenic helminth …