Strategies for Improving Aptamer Screening Efficiency: Library Design, Awareness Innovation, and Instrument Assistance
Y Zhang, S Zhang, Z Ning, M Duan, X Lin… - Critical Reviews in …, 2024 - Taylor & Francis
Aptamers, as short single-stranded nucleic acids, can bind to targets in a similar way to
antibodies. Relying on the advantages of low cost, high stability, and flexibility, they are …
antibodies. Relying on the advantages of low cost, high stability, and flexibility, they are …
Recent advances in design strategies of aptamer‐based liquid biopsy
B Lin, JT Jiang, X Zhou - Journal of Polymer Science, 2024 - Wiley Online Library
Liquid biopsy represents a groundbreaking technology enabling the detection, analysis, and
monitoring of circulating targets in body fluids, such as blood, to acquire crucial molecular …
monitoring of circulating targets in body fluids, such as blood, to acquire crucial molecular …
Triple multivalent aptamers within DNA tetrahedron on reduced graphene oxide electrode: Unlocking enhanced sensitivity and accelerated reactions in …
DNA nanostructures are emerging as promising biosensing platforms due to their
programmability, predictable assembly, and compatibility with aptamers for enhanced …
programmability, predictable assembly, and compatibility with aptamers for enhanced …
Polyvalent Aptamers Structure-Mediated Fluorescent Aptasensor for the Early Diagnosis of Alzheimer's Disease by Coupling with HCR and CRISPR-Cas System
X Li, B Chen, Y Xie, Y Luo, D Zhu, L Wang… - Analytical …, 2024 - ACS Publications
The early diagnosis of Alzheimer's disease (AD) plays a vital role in slowing the progression
of AD and improving the quality of human life. However, it is still a challenge in the medical …
of AD and improving the quality of human life. However, it is still a challenge in the medical …
Dimeric DNA Aptamers for the Spike Protein of SARS‐CoV‐2 Derived from a Structured Library with Dual Random Domains
Multimeric aptamer strategies are often adopted to improve the binding affinity of an aptamer
toward its target molecules. In most cases, multimeric aptamers are constructed by …
toward its target molecules. In most cases, multimeric aptamers are constructed by …
Recent Advances in DNA Nanotechnology‐Based Sensing Platforms for Rapid Virus Detection
Y Dong, C Guo, J Wang, C Ye, Q Min - ChemBioChem, 2024 - Wiley Online Library
Several major viral pandemics in history have significantly impacted the public health of
human beings. The COVID‐19 pandemic has further underscored the critical need for early …
human beings. The COVID‐19 pandemic has further underscored the critical need for early …
NF2 regulates IP3R‐mediated Ca2+ signal and apoptosis in meningiomas
Z Lei, J Niu, H Cai, Z Kong, X Ding, Y Dong… - The FASEB …, 2024 - Wiley Online Library
Meningiomas are the most common primary intracranial tumors and account for nearly 30%
of all nervous system tumors. Approximately half of meningioma patients exhibit …
of all nervous system tumors. Approximately half of meningioma patients exhibit …