Strategies for Improving Aptamer Screening Efficiency: Library Design, Awareness Innovation, and Instrument Assistance

Y Zhang, S Zhang, Z Ning, M Duan, X Lin… - Critical Reviews in …, 2024 - Taylor & Francis
Aptamers, as short single-stranded nucleic acids, can bind to targets in a similar way to
antibodies. Relying on the advantages of low cost, high stability, and flexibility, they are …

Recent advances in design strategies of aptamer‐based liquid biopsy

B Lin, JT Jiang, X Zhou - Journal of Polymer Science, 2024 - Wiley Online Library
Liquid biopsy represents a groundbreaking technology enabling the detection, analysis, and
monitoring of circulating targets in body fluids, such as blood, to acquire crucial molecular …

Triple multivalent aptamers within DNA tetrahedron on reduced graphene oxide electrode: Unlocking enhanced sensitivity and accelerated reactions in …

SJ Jang, TH Kim - Biosensors and Bioelectronics, 2024 - Elsevier
DNA nanostructures are emerging as promising biosensing platforms due to their
programmability, predictable assembly, and compatibility with aptamers for enhanced …

Polyvalent Aptamers Structure-Mediated Fluorescent Aptasensor for the Early Diagnosis of Alzheimer's Disease by Coupling with HCR and CRISPR-Cas System

X Li, B Chen, Y Xie, Y Luo, D Zhu, L Wang… - Analytical …, 2024 - ACS Publications
The early diagnosis of Alzheimer's disease (AD) plays a vital role in slowing the progression
of AD and improving the quality of human life. However, it is still a challenge in the medical …

Dimeric DNA Aptamers for the Spike Protein of SARS‐CoV‐2 Derived from a Structured Library with Dual Random Domains

R Amini, J Ma, Z Zhang, Q Wang, J Gu… - Small …, 2024 - Wiley Online Library
Multimeric aptamer strategies are often adopted to improve the binding affinity of an aptamer
toward its target molecules. In most cases, multimeric aptamers are constructed by …

Recent Advances in DNA Nanotechnology‐Based Sensing Platforms for Rapid Virus Detection

Y Dong, C Guo, J Wang, C Ye, Q Min - ChemBioChem, 2024 - Wiley Online Library
Several major viral pandemics in history have significantly impacted the public health of
human beings. The COVID‐19 pandemic has further underscored the critical need for early …

NF2 regulates IP3R‐mediated Ca2+ signal and apoptosis in meningiomas

Z Lei, J Niu, H Cai, Z Kong, X Ding, Y Dong… - The FASEB …, 2024 - Wiley Online Library
Meningiomas are the most common primary intracranial tumors and account for nearly 30%
of all nervous system tumors. Approximately half of meningioma patients exhibit …