Anionic lipids act as signals for the recruitment of proteins containing cationic clusters to
biological membranes. A family of anionic lipids known as the phosphoinositides (PIPs) are …

Located at the inner leaflet of the plasma membrane (PM), phosphatidyl-inositol 4, 5-
bisphosphate [PI (4, 5) P2] composes only 1–2 mol% of total PM lipids. With its synthesis …

Membrane lipids play vital roles in small extracellular vesicle (sEV) biogenesis. However,
the function of various lipids in the biogenesis of sEVs is still poorly understood …

Septins are conserved cytoskeletal proteins that regulate cell cortex mechanics. The
mechanisms of their interactions with the plasma membrane remain poorly understood …

Organization of dynamic cellular structure is crucial for a variety of cellular functions. In this
study, we report that Drosophila and Aedes have highly elastic cell membranes with …

Phosphatidic acid (PA) is a crucial membrane phospholipid involved in de novo lipid
synthesis and numerous intracellular signaling cascades. The signaling function of PA is …

Abstract Phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P 2 or PIP2), is a key component of
the inner leaflet of the plasma membrane in eukaryotic cells. In model membranes, PIP2 has …

All-atom molecular dynamics simulations combined with graph–theoretic analysis reveal
that clustering of monomethyl phosphate dianion (MMP2–) is strongly influenced by the …

The retroviral polyprotein Gag is an essential component for the formation of virus in infected
cells. HIV-1 Gag is expressed in the cytoplasm, migrates to the cellular periphery and …

The cell membrane serves, at the same time, both as a barrier that segregates as well as a
functional layer that facilitates selective communication. It is characterized as much by the …