This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-
lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug …

Cellular redox status has been considered as a focal point for the pathogenesis of multiple
disorders. High and persistent levels of free radicals kick off inflammation and associated …

β-Lapachone is an ortho-naphthoquinone natural product with significant antiproliferative
activity but suffers from adverse systemic toxicity. The use of photoremovable protecting …

Abstract β-Lapachone is a classic quinone-containing antitumor NQO1-bioactivatable drug
that directly kills NQO1-overexpressing cancer cells. However, the clinical applications of β …

Inflammation plays a significant role in the pathogenesis of chronic diseases. Inflammatory
diseases such as bacterial diseases, Alzheimer's disease, rheumatoid arthritis, multiple …

Abstract Background MiR-452-5p has been reported to be down-regulated in prostate
cancer, affecting the development of this type of cancer. However, the molecular mechanism …

Abstract The natural compound 1, 4-naphthoquinone has potent anti-tumor activity.
However, the clinical application of 1, 4-naphthoquinone and its derivatives has been limited …

Background/Aim: Numerous evidence has shown that PEITC and BITC inhibit cancer cell
migration and invasion. In this study, we investigated the anti-metastatic mechanisms of …

Gomisin A (GA) is a dietary lignan compound from Schisandra chinensis. In this study, the
effect of GA on the proliferation and metastasis of colorectal cancer (CRC) cells was …

Abstract β-Lapachone is a natural naphthoquinone originally obtained from the bark of the
purple Ipe (Tabebuia avellanedae Lor, Bignoniaceae) and its therapeutic potential in human …