Gut Microbiota and Its Role in the Brain-Gut-Kidney Axis in Hypertension

NG Vallianou, D Kounatidis, F Panagopoulos… - Current Hypertension …, 2023 - Springer
Abstract Purpose of Review The role of the gut microbiota in modulating blood pressure is
increasingly being recognized, currently. The purpose of this review is to summarize recent …

Diagnostic value of soluble urokinase‐type plasminogen activator receptor in patients with acute coronary syndrome: A systematic review and meta-analysis

M Pruc, I Jannisz, D Swieczkowski… - Cardiology …, 2023 - journals.viamedica.pl
Background: In contemporary clinical practice, there is an increasing need for new clinically
relevant biomarkers potentially optimizing management strategies in patients with suspected …

Soluble urokinase plasminogen activator receptor: From biomarker to active participant in atherosclerosis and cardiovascular disease

TT Goodchild, Z Li, DJ Lefer - The Journal of Clinical …, 2022 - Am Soc Clin Investig
Atherosclerosis contributes to the majority of deaths related to cardiovascular disease
(CVD). Recently, the nonspecific inflammatory biomarker soluble urokinase plasminogen …

The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease

K Zhu, K Mukherjee, C Wei, SS Hayek… - Science Translational …, 2023 - science.org
Soluble urokinase plasminogen activator receptor (suPAR) is a risk factor for kidney
diseases. In addition to suPAR, proteolysis of membrane-bound uPAR results in circulating …

Immune activation mediates the Association of Advanced Hepatic Fibrosis with Adverse Outcomes in patients with coronary artery disease

V Jain, A Mehta, TB Lee, C Liu, NWS Chew… - Journal of the …, 2023 - Am Heart Assoc
Background Literature suggests a bidirectional association between advanced hepatic
fibrosis (AHF) and coronary artery disease (CAD). We evaluated the association of AHF with …

Gut microbiome and cardiometabolic comorbidities in people living with HIV

M Trøseid, SD Nielsen, I Vujkovic-Cvijin - Microbiome, 2024 - Springer
Background Despite modern antiretroviral therapy (ART), people living with HIV (PLWH)
have increased relative risk of inflammatory-driven comorbidities, including cardiovascular …

Obesity, Inflammation, and Clinical Outcomes in COVID-19: A Multicenter Prospective Cohort Study

CG Hutten, K Padalia, A Vasbinder… - The Journal of …, 2024 - academic.oup.com
Context Obesity is a risk factor for coronavirus disease 2019 (COVID-19)-related outcomes;
however, the mechanism remains unclear. Objective The objective of this analysis was to …

Overall and inter‐individual effect of four different drug classes on soluble urokinase plasminogen activator receptor in type 1 and type 2 diabetes

V Rotbain Curovic, MB Houlind… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To evaluate the effect of four different drug classes on soluble urokinase plasminogen
activator receptor (suPAR), a biomarker active in multiple inflammatory processes and a risk …

Venous Thromboembolic Disease Genetics: From variants to function

M Underwood, C Bidlack, KC Desch - Journal of Thrombosis and …, 2024 - Elsevier
Venous thromboembolic disease (VTE) is a prevalent and potentially life-threatening
vascular disease including both deep vein thrombosis and pulmonary embolism. This …

Multi-proteomic Biomarker Risk Scores for Predicting Risk and Guiding Therapy in Patients with Coronary Artery Disease

ME Gold, E Woods, D Pobee, R Ibrahim… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review Patients with established coronary artery disease (CAD) are at
high residual risk for adverse events, despite guideline-based treatments. Herein, we aimed …