Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions

JD Lasso, DJ Castillo-Pazos, CJ Li - Chemical Society Reviews, 2021 - pubs.rsc.org
The progress of drug discovery and development is paced by milestones reached in organic
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …

Selective decarbonylation via transition-metal-catalyzed carbon–carbon bond cleavage

H Lu, TY Yu, PF Xu, H Wei - Chemical Reviews, 2020 - ACS Publications
Transition-metal-catalyzed decarbonylation via carbon–carbon bond cleavage is an
essential synthetic methodology. Given the ubiquity of carbonyl compounds, the selective …

Nanoarchitectonics: what's coming next after nanotechnology?

K Ariga - Nanoscale Horizons, 2021 - pubs.rsc.org
In science and technology today, the crucial importance of the regulation of nanoscale
objects and structures is well recognized. The production of functional material systems …

Aroyl fluorides as bifunctional reagents for dearomatizing fluoroaroylation of benzofurans

X Yu, QY Meng, CG Daniliuc… - Journal of the American …, 2022 - ACS Publications
The 2, 3-dihydrobenzofuran scaffold is widely found in natural products and biologically
active compounds. Herein, dearomatizing 2, 3-fluoroaroylation of benzofurans with aroyl …

A single‐atom cobalt catalyst for the fluorination of acyl chlorides at parts‐per‐million catalyst loading

WH Li, BC Ye, J Yang, Y Wang, CJ Yang… - Angewandte Chemie …, 2022 - Wiley Online Library
Improving the stability of sensitive catalytic systems is an emerging research topic in the
catalysis field. However, the current design of heterogeneous catalysts mainly improves their …

Synthetic Advantages of Defluorinative C− F Bond Functionalization

LV Hooker, JS Bandar - Angewandte Chemie, 2023 - Wiley Online Library
Much progress has been made in the development of methods to both create compounds
that contain C− F bonds and to functionalize C− F bonds. As such, C− F bonds are becoming …

Solid‐State Radical C− H Trifluoromethylation Reactions Using Ball Milling and Piezoelectric Materials

Y Pang, JW Lee, K Kubota, H Ito - … Chemie International Edition, 2020 - Wiley Online Library
The application of piezoelectricity for the generation of trifluoromethyl (CF3) radicals is
reported together with the development of a method for the mechanochemical C− H …

Repurposing of F-gases: challenges and opportunities in fluorine chemistry

DJ Sheldon, MR Crimmin - Chemical Society Reviews, 2022 - pubs.rsc.org
Fluorinated gases (F-gases) are routinely employed as refrigerants, blowing agents, and
electrical insulators. These volatile compounds are potent greenhouse gases and …

Nanoarchitectonics for coordination asymmetry and related chemistry

K Ariga, M Shionoya - Bulletin of the Chemical Society of Japan, 2021 - academic.oup.com
Nanoarchitectonics is a concept envisioned to produce functional materials from nanoscale
units through fusion of nanotechnology with other scientific disciplines. For component …

Facile synthesis of bimetallic fluoride heterojunctions on defect-enriched porous carbon nanofibers for efficient ORR catalysts

J Yan, Y Huang, Y Zhang, W Peng, S Xia, J Yu… - Nano …, 2021 - ACS Publications
The development of efficient and stable catalysts for the oxygen reduction reaction (ORR) at
low cost is crucial for realizing the large-scale application of metal–air batteries. Herein, we …