Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions
The progress of drug discovery and development is paced by milestones reached in organic
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …
Selective decarbonylation via transition-metal-catalyzed carbon–carbon bond cleavage
H Lu, TY Yu, PF Xu, H Wei - Chemical Reviews, 2020 - ACS Publications
Transition-metal-catalyzed decarbonylation via carbon–carbon bond cleavage is an
essential synthetic methodology. Given the ubiquity of carbonyl compounds, the selective …
essential synthetic methodology. Given the ubiquity of carbonyl compounds, the selective …
Nanoarchitectonics: what's coming next after nanotechnology?
K Ariga - Nanoscale Horizons, 2021 - pubs.rsc.org
In science and technology today, the crucial importance of the regulation of nanoscale
objects and structures is well recognized. The production of functional material systems …
objects and structures is well recognized. The production of functional material systems …
Aroyl fluorides as bifunctional reagents for dearomatizing fluoroaroylation of benzofurans
X Yu, QY Meng, CG Daniliuc… - Journal of the American …, 2022 - ACS Publications
The 2, 3-dihydrobenzofuran scaffold is widely found in natural products and biologically
active compounds. Herein, dearomatizing 2, 3-fluoroaroylation of benzofurans with aroyl …
active compounds. Herein, dearomatizing 2, 3-fluoroaroylation of benzofurans with aroyl …
A single‐atom cobalt catalyst for the fluorination of acyl chlorides at parts‐per‐million catalyst loading
Improving the stability of sensitive catalytic systems is an emerging research topic in the
catalysis field. However, the current design of heterogeneous catalysts mainly improves their …
catalysis field. However, the current design of heterogeneous catalysts mainly improves their …
Synthetic Advantages of Defluorinative C− F Bond Functionalization
LV Hooker, JS Bandar - Angewandte Chemie, 2023 - Wiley Online Library
Much progress has been made in the development of methods to both create compounds
that contain C− F bonds and to functionalize C− F bonds. As such, C− F bonds are becoming …
that contain C− F bonds and to functionalize C− F bonds. As such, C− F bonds are becoming …
Solid‐State Radical C− H Trifluoromethylation Reactions Using Ball Milling and Piezoelectric Materials
The application of piezoelectricity for the generation of trifluoromethyl (CF3) radicals is
reported together with the development of a method for the mechanochemical C− H …
reported together with the development of a method for the mechanochemical C− H …
Repurposing of F-gases: challenges and opportunities in fluorine chemistry
DJ Sheldon, MR Crimmin - Chemical Society Reviews, 2022 - pubs.rsc.org
Fluorinated gases (F-gases) are routinely employed as refrigerants, blowing agents, and
electrical insulators. These volatile compounds are potent greenhouse gases and …
electrical insulators. These volatile compounds are potent greenhouse gases and …
Nanoarchitectonics for coordination asymmetry and related chemistry
K Ariga, M Shionoya - Bulletin of the Chemical Society of Japan, 2021 - academic.oup.com
Nanoarchitectonics is a concept envisioned to produce functional materials from nanoscale
units through fusion of nanotechnology with other scientific disciplines. For component …
units through fusion of nanotechnology with other scientific disciplines. For component …
Facile synthesis of bimetallic fluoride heterojunctions on defect-enriched porous carbon nanofibers for efficient ORR catalysts
J Yan, Y Huang, Y Zhang, W Peng, S Xia, J Yu… - Nano …, 2021 - ACS Publications
The development of efficient and stable catalysts for the oxygen reduction reaction (ORR) at
low cost is crucial for realizing the large-scale application of metal–air batteries. Herein, we …
low cost is crucial for realizing the large-scale application of metal–air batteries. Herein, we …